{"id":"W4361953411","doi":"10.1158/1078-0432.c.6529767.v1","title":"Data from Phase Ib Dose-escalation/Expansion Trial of Ribociclib in Combination With Everolimus and Exemestane in Postmenopausal Women with HR<sup>+</sup>, HER2<sup>−</sup> Advanced Breast Cancer","year":2023,"lang":"en","type":"preprint","venue":"","topic":"Advanced Breast Cancer Therapies","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Institute of Cancer Research","funders":"","keywords":"Medicine; Everolimus; Exemestane; Internal medicine; Tolerability; Breast cancer; Adverse effect; Oncology; Cancer; Gastroenterology; Aromatase","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001744913,0.001066519,0.001874163,0.0003076474,0.0005225064,0.001113129,0.0007452125,0.00102382,0.005113103],"category_scores_gemma":[0.001188912,0.0004500444,0.001022091,0.0006728984,0.0006278753,0.001031348,0.0003035846,0.002846363,0.00135163],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0009343027,"about_ca_system_score_gemma":0.001840736,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001533024,"about_ca_topic_score_gemma":0.004210071,"domain_scores_codex":[0.9994271,0.0002356961,0.00006201737,0.00008328113,0.0001086259,0.00008323023],"domain_scores_gemma":[0.9988441,0.0002114839,0.0002471055,0.0001805581,0.0001156639,0.0004011449],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"nonrandomized_trial","study_design_scores_codex":[0.6392197,0.03053628,0.01660341,0.00192376,0.003327816,0.0005393657,0.0003541799,0.006620675,0.0656819,0.0006361482,0.04501055,0.1895462],"study_design_scores_gemma":[0.5387058,0.3191757,0.06882463,0.000236944,0.003283125,0.00141436,0.0002067683,0.002554026,0.02044774,0.001088048,0.04394938,0.0001134256],"study_design_candidate":"nonrandomized_trial","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"dataset","genre_scores_codex":[0.9382477,0.004776256,0.001583125,0.002052835,0.0003047033,0.005725347,0.03131415,0.0002874527,0.01570846],"genre_scores_gemma":[0.928646,0.003219851,0.003160439,0.003911489,0.0002154754,0.006125516,0.0462941,0.000118172,0.008308921],"genre_candidate":"dataset","genre_consensus":null,"teacher_disagreement_score":0.005113103,"threshold_uncertainty_score":0.01710498,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0286051356831239,"score_gpt":0.3199529618484541,"score_spread":0.2913478261653302,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}