{"id":"W4361953852","doi":"10.1158/1078-0432.c.6529353.v1","title":"Data from Entospletinib in Combination with Induction Chemotherapy in Previously Untreated Acute Myeloid Leukemia: Response and Predictive Significance of <i>HOXA9</i> and <i>MEIS1</i> Expression","year":2023,"lang":"en","type":"preprint","venue":"","topic":"Acute Myeloid Leukemia Research","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Princess Margaret Cancer Centre","funders":"Gilead Sciences","keywords":"Medicine; Cytarabine; Internal medicine; Myeloid leukemia; Gastroenterology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001436896,0.0006486612,0.001382698,0.0003007193,0.0002534339,0.0007131164,0.0004811562,0.0006885687,0.002276925],"category_scores_gemma":[0.001294794,0.000211469,0.0009812439,0.00048635,0.0004773633,0.0007216003,0.0002354178,0.001486648,0.0005835946],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0008113145,"about_ca_system_score_gemma":0.0006292795,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000770628,"about_ca_topic_score_gemma":0.002786298,"domain_scores_codex":[0.9993601,0.0002569827,0.00007514857,0.0001081699,0.00013025,0.00006931395],"domain_scores_gemma":[0.9984825,0.0004349918,0.0004495817,0.0002123459,0.000103223,0.0003173533],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"observational","study_design_scores_codex":[0.5846829,0.01021217,0.08006776,0.001350438,0.003551793,0.0006318092,0.0003974715,0.00837821,0.06408081,0.0004097889,0.009841391,0.2363954],"study_design_scores_gemma":[0.1134202,0.357445,0.4490616,0.0002828148,0.004719637,0.00295405,0.0002827579,0.00623895,0.037319,0.0006109072,0.02748445,0.0001805155],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"dataset","genre_scores_codex":[0.9902449,0.002927018,0.0003853432,0.0003568175,0.00006396695,0.0003088231,0.002511569,0.00005746541,0.003144159],"genre_scores_gemma":[0.9923263,0.0009845047,0.0002886092,0.0003657996,0.00005777168,0.0002057069,0.004413306,0.00001878658,0.001339209],"genre_candidate":"dataset","genre_consensus":null,"teacher_disagreement_score":0.002276925,"threshold_uncertainty_score":0.007617056,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03237606889949094,"score_gpt":0.2971865765427594,"score_spread":0.2648105076432684,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}