{"id":"W4361954030","doi":"10.1158/1535-7163.c.6531606.v1","title":"Data from Garcinol Potentiates TRAIL-Induced Apoptosis through Modulation of Death Receptors and Antiapoptotic Proteins","year":2023,"lang":"en","type":"preprint","venue":"","topic":"Cell death mechanisms and regulation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Institute of Cancer Research","funders":"National Institutes of Health","keywords":"Chemistry; Apoptosis; Survivin; XIAP; Receptor; Cell biology; Programmed cell death; Biology; Biochemistry; Caspase","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001449838,0.0004757405,0.0003579133,0.0003929634,0.0001619028,0.0002056824,0.0002476809,0.000326527,0.004920944],"category_scores_gemma":[0.0001452225,0.0001037835,0.0004496522,0.0002855547,0.0001916518,0.0001899265,0.0001077088,0.0006054868,0.001012847],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002748134,"about_ca_system_score_gemma":0.0002060868,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000683261,"about_ca_topic_score_gemma":0.0007993144,"domain_scores_codex":[0.9998627,0.00002442481,0.00001960845,0.00001485576,0.00004895732,0.00002942881],"domain_scores_gemma":[0.9998935,0.00002402588,0.00002462242,0.00001690458,0.00001763995,0.00002325024],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.004072436,0.0002480716,0.0005713947,0.0005056454,0.00007111859,0.0004524961,0.00004748063,0.000188431,0.9802104,0.0003171538,0.0009581805,0.01235721],"study_design_scores_gemma":[0.0002764908,0.002422065,0.01052392,0.0000230711,0.0001301879,0.0006918139,0.00003768436,0.000381315,0.9717559,0.0001048376,0.01363716,0.00001555444],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"dataset","genre_scores_codex":[0.9661222,0.01202549,0.002148554,0.0007231997,0.0003195096,0.000109891,0.005476477,0.0004297257,0.012645],"genre_scores_gemma":[0.9825133,0.004633607,0.001296624,0.0003196805,0.0001047449,0.00007548335,0.004552595,0.00002439598,0.006479669],"genre_candidate":"dataset","genre_consensus":null,"teacher_disagreement_score":0.004920944,"threshold_uncertainty_score":0.01646215,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.08394145531861182,"score_gpt":0.2964663399675991,"score_spread":0.2125248846489873,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}