{"id":"W4361959406","doi":"10.1158/1078-0432.c.6529556","title":"Data from Baseline Characteristics, Treatment Patterns, and Outcomes in Patients with HER2-Positive Metastatic Breast Cancer by Hormone Receptor Status from SystHERs","year":2023,"lang":"en","type":"preprint","venue":"","topic":"Advanced Breast Cancer Therapies","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Roche (Canada)","funders":"Genentech; F. Hoffmann-La Roche","keywords":"Medicine; Hazard ratio; Internal medicine; Metastatic breast cancer; Breast cancer; Chemotherapy; Population; Oncology; Gastroenterology; Confidence interval; Cancer; Gynecology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0001161654,0.0008017035,0.001655709,0.0001487024,0.00004407524,0.00007321549,0.0002752987,0.0001632999,0.0006570065],"category_scores_gemma":[0.00003806551,0.0005571038,0.00006440469,0.0001028388,0.0001215488,0.000187865,0.0005171394,0.000443453,0.00002938751],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001113884,"about_ca_system_score_gemma":0.0002789296,"about_ca_topic_candidate":true,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.1293229,"about_ca_topic_score_gemma":0.007687887,"domain_scores_codex":[0.9965492,0.000173451,0.0006937218,0.001505825,0.0005443536,0.0005333783],"domain_scores_gemma":[0.9973058,0.0003283459,0.0004539151,0.001394696,0.000191739,0.0003254836],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.003559468,0.0009573185,0.9465414,0.0001104986,0.003333855,0.00004487642,0.0006475139,0.000009428547,0.00006580457,3.349933e-7,0.0004949485,0.04423459],"study_design_scores_gemma":[0.008690067,0.0003628147,0.9865487,0.001339734,0.0009445269,9.798229e-7,0.0005991772,0.0002745271,0.00005222328,0.00001862802,0.0005948173,0.0005737676],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.6657934,0.00111844,0.001195991,0.001281365,0.0002600232,0.001381602,0.3288571,0.0001091894,0.00000295357],"genre_scores_gemma":[0.8032108,0.004849271,0.005348806,0.0007125746,0.0002496302,0.0005741954,0.1839535,0.0003038025,0.0007974076],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1449035,"threshold_uncertainty_score":0.999688,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02691742840883151,"score_gpt":0.2995488053940495,"score_spread":0.272631376985218,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}