{"id":"W4361959639","doi":"10.1158/1078-0432.c.6526599","title":"Data from Neoadjuvant Chemotherapy of Ovarian Cancer Results in Three Patterns of Tumor-Infiltrating Lymphocyte Response with Distinct Implications for Immunotherapy","year":2023,"lang":"en","type":"preprint","venue":"","topic":"Cancer Immunotherapy and Biomarkers","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Victoria; Université de Moncton; University Health Network; University of British Columbia; BC Cancer Agency","funders":"","keywords":"Tumor-infiltrating lymphocytes; Immune system; CD8; Chemotherapy; Medicine; Cancer research; Internal medicine; Immunology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002063274,0.0001538985,0.000212323,0.000287447,0.0001310037,0.0002435536,0.0000833856,0.0001581294,0.002933724],"category_scores_gemma":[0.0006375475,0.00009519725,0.0001738855,0.0002716458,0.0002125365,0.0001597185,0.0001848921,0.0002498064,0.0005671637],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001771768,"about_ca_system_score_gemma":0.0001548756,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002896506,"about_ca_topic_score_gemma":0.0005399905,"domain_scores_codex":[0.999843,0.00003918171,0.00002694934,0.00002834525,0.00004100772,0.00002148894],"domain_scores_gemma":[0.9994522,0.0001752969,0.0001402209,0.00009754983,0.00004407087,0.0000906123],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.01067029,0.0003123308,0.557255,0.000304328,0.00008747992,0.0007462553,0.0002398207,0.0004067218,0.3879632,0.0001126021,0.0009126642,0.04098926],"study_design_scores_gemma":[0.00008750854,0.001432728,0.9683349,0.00001112769,0.00006061175,0.002281931,0.0001287502,0.0002414965,0.02471669,0.00006480824,0.002633131,0.000006265944],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"dataset","genre_scores_codex":[0.9958909,0.0005613337,0.0002841193,0.00006650405,0.000007626992,0.0000231317,0.0005848908,0.00002302869,0.002558568],"genre_scores_gemma":[0.9981722,0.000152092,0.0001827562,0.00004343665,0.000005680785,0.00003364138,0.0009774696,0.000006555964,0.0004260908],"genre_candidate":"dataset","genre_consensus":null,"teacher_disagreement_score":0.002933724,"threshold_uncertainty_score":0.009814262,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.08533555148204584,"score_gpt":0.3544894738158662,"score_spread":0.2691539223338204,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}