{"id":"W4361959681","doi":"10.1158/1078-0432.c.6530078","title":"Data from CEACAM7 Is an Effective Target for CAR T-cell Therapy of Pancreatic Ductal Adenocarcinoma","year":2023,"lang":"en","type":"preprint","venue":"","topic":"CAR-T cell therapy research","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia; BC Cancer Agency","funders":"Cancer Research UK; Pancreatic Cancer UK; Johns Hopkins University; Canary Foundation","keywords":"Cancer research; Pancreatic cancer; In vivo; Adenocarcinoma; Pancreas; Cell culture; Pancreatic ductal adenocarcinoma; In vitro; Cancer; Medicine; Biology; Internal medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002949861,0.0003163003,0.0004423171,0.0003961626,0.0001666738,0.000465952,0.0002969112,0.0004323419,0.008719319],"category_scores_gemma":[0.0002322763,0.0001393945,0.0004018869,0.0002967496,0.0002057813,0.0002347174,0.0001462908,0.0009012832,0.001918652],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003619936,"about_ca_system_score_gemma":0.0003321869,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008492238,"about_ca_topic_score_gemma":0.001042504,"domain_scores_codex":[0.999727,0.00004644397,0.00003497793,0.00004252329,0.0001110631,0.00003809568],"domain_scores_gemma":[0.9997781,0.00006126599,0.00002361176,0.00003629931,0.00005074471,0.00004996351],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00160434,0.0004192777,0.001296935,0.0004778267,0.0000574996,0.0002232493,0.00003898291,0.0002718521,0.9739388,0.0003680763,0.003580036,0.01772326],"study_design_scores_gemma":[0.0002853075,0.003813016,0.01029786,0.00003478519,0.000184,0.00112986,0.00007159573,0.001055055,0.9456084,0.0001657879,0.03734178,0.00001258878],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"dataset","genre_scores_codex":[0.9206787,0.01438701,0.008900388,0.001801806,0.0003461134,0.0004059947,0.01037375,0.000690719,0.04241544],"genre_scores_gemma":[0.9566109,0.007025815,0.003575925,0.001105941,0.00009411737,0.0003067499,0.01251137,0.0001560157,0.01861324],"genre_candidate":"dataset","genre_consensus":null,"teacher_disagreement_score":0.008719319,"threshold_uncertainty_score":0.02916902,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1388699863816797,"score_gpt":0.3811469021155344,"score_spread":0.2422769157338547,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}