{"id":"W4362414827","doi":"10.1158/1078-0432.22482735","title":"Supplementary Figure S2 from Safety and Antitumor Activity of α-PD-L1 Antibody as Monotherapy or in Combination with α-TIM-3 Antibody in Patients with Microsatellite Instability–High/Mismatch Repair–Deficient Tumors","year":2023,"lang":"en","type":"preprint","venue":"","topic":"Genetic factors in colorectal cancer","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Princess Margaret Cancer Centre","funders":"","keywords":"Microsatellite instability; Antibody; Medicine; Oncology; Internal medicine; Cancer research; Microsatellite; Biology; Immunology; Genetics; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0008149442,0.001284594,0.0009975714,0.0009692421,0.0007418689,0.001161126,0.001207693,0.001083342,0.7607681],"category_scores_gemma":[0.00512968,0.0005615919,0.001409968,0.0008859256,0.0002353392,0.0007405049,0.0004165548,0.001575211,0.1244666],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001216545,"about_ca_system_score_gemma":0.002280751,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.005689119,"about_ca_topic_score_gemma":0.01137311,"domain_scores_codex":[0.9994313,0.0000681467,0.00005216933,0.00009810449,0.0002557377,0.00009437784],"domain_scores_gemma":[0.9959837,0.001989082,0.0003148478,0.0002389313,0.0008974296,0.0005759142],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"nonrandomized_trial","study_design_scores_codex":[0.001749816,0.0002021274,0.0006884474,0.0009418004,0.0001143607,0.0001702662,0.00001594418,0.0004061365,0.002193748,0.0009138726,0.9784943,0.01410926],"study_design_scores_gemma":[0.008777051,0.002060473,0.03038562,0.001119175,0.000294599,0.002236509,0.000135966,0.003203362,0.009342215,0.007266259,0.9350572,0.0001215047],"study_design_candidate":"nonrandomized_trial","study_design_consensus":null,"genre_codex":"dataset","genre_gemma":"dataset","genre_scores_codex":[0.003921978,0.0009512769,0.002092246,0.002936782,0.004846192,0.0003217206,0.9662202,0.001583321,0.01712626],"genre_scores_gemma":[0.04125563,0.0023942,0.01376374,0.005184922,0.002652527,0.00224883,0.8550575,0.00155707,0.07588564],"genre_candidate":"dataset","genre_consensus":"dataset","teacher_disagreement_score":0.7607681,"threshold_uncertainty_score":0.3412352,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01334643139093695,"score_gpt":0.2881689873854604,"score_spread":0.2748225559945235,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}