{"id":"W4362459260","doi":"10.2217/fon-2022-1035","title":"Plain language summary of the development of tepotinib: a treatment for a subtype of non-small cell lung cancer called <i>MET</i> exon 14 skipping","year":2023,"lang":"en","type":"article","venue":"Future Oncology","topic":"Lung Cancer Treatments and Mutations","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Trinity College","funders":"","keywords":"Medicine; Lung cancer; Exon; Cancer; Targeted therapy; Oncology; Cancer research; Internal medicine; Mutation; Exon skipping; Genetics; Gene; Biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001315375,0.0009555325,0.001472429,0.001473039,0.0006146969,0.003005084,0.001262233,0.002631412,0.1811276],"category_scores_gemma":[0.009799188,0.0003748708,0.001229349,0.001286008,0.0004674093,0.002699,0.0009254982,0.003247682,0.1065891],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001475814,"about_ca_system_score_gemma":0.00246837,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0036867,"about_ca_topic_score_gemma":0.003624,"domain_scores_codex":[0.9988669,0.0002568353,0.000257306,0.0001110336,0.0004150771,0.0000928806],"domain_scores_gemma":[0.9943531,0.001719458,0.0008141234,0.000112125,0.002592651,0.0004086254],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001253087,0.00001533711,0.00005871,0.001257151,0.000007234215,0.0001139279,0.0000188559,0.00004604475,0.0004049151,0.0007312931,0.9597888,0.0374324],"study_design_scores_gemma":[0.00002666831,0.00006250374,0.0002032832,0.0006890391,0.00001285736,0.000225799,0.00001726947,0.00002555184,0.0001925326,0.0003146918,0.9982215,0.000008452042],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"other","genre_gemma":"other","genre_scores_codex":[0.002081089,0.1862288,0.008168519,0.2393467,0.1424647,0.001610405,0.07404765,0.0027709,0.3432811],"genre_scores_gemma":[0.01156477,0.186629,0.005660165,0.197074,0.06403924,0.001549591,0.05034373,0.001695076,0.4814445],"genre_candidate":"other","genre_consensus":"other","teacher_disagreement_score":0.1811276,"threshold_uncertainty_score":0.6059322,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01721009959239901,"score_gpt":0.3518645917047744,"score_spread":0.3346544921123754,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}