{"id":"W4362466996","doi":"10.3390/cells12071059","title":"Primary Cilium Identifies a Quiescent Cell Population in the Human Intestinal Crypt","year":2023,"lang":"en","type":"article","venue":"Cells","topic":"Genetic and Kidney Cyst Diseases","field":"Biochemistry, Genetics and Molecular Biology","cited_by":7,"is_retracted":false,"has_abstract":true,"ca_institutions":"Centre Hospitalier Universitaire de Sherbrooke; Université de Sherbrooke","funders":"Canadian Institutes of Health Research; Natural Sciences and Engineering Research Council of Canada; Genentech; Turun Yliopisto","keywords":"Cilium; Biology; Crypt; Cell biology; Population; Progenitor cell; Stem cell; Paneth cell; Cell; Epithelium; Cellular differentiation; Pathology; Anatomy; Small intestine; Genetics; Endocrinology; Medicine; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000150388,0.00008768006,0.00006789475,0.0000393197,0.00006678957,0.00002999951,0.0001760205,0.00004893646,0.00002007851],"category_scores_gemma":[0.00002272427,0.0000700681,0.00005334836,0.0001161639,0.00003618145,0.000001796915,0.00007832644,0.00004969279,0.0000728372],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000008721814,"about_ca_system_score_gemma":0.00002875257,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00005016764,"about_ca_topic_score_gemma":0.00002244827,"domain_scores_codex":[0.999316,0.00006038415,0.0001389967,0.0001932033,0.000115218,0.0001761546],"domain_scores_gemma":[0.9996585,0.0000102999,0.00003590927,0.0002350518,0.00001912033,0.00004115406],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.000009434762,0.00006082989,0.0095118,0.00005092952,0.000003277079,0.000008157514,0.0001191248,0.00005729257,0.9637513,0.000007260434,0.02628528,0.0001352999],"study_design_scores_gemma":[0.000453155,0.0001106051,0.5280694,0.00002648232,0.00002089441,0.000003808876,0.0006517057,0.00002829979,0.4612595,0.0004590513,0.008708999,0.0002081504],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9969836,0.0002267941,0.00003162057,0.0001030833,0.0001331393,0.0001489677,0.000009168417,0.00001477904,0.002348846],"genre_scores_gemma":[0.9972633,0.0000441777,0.00003653621,0.0003396404,0.0001231037,0.00002046319,0.0003974779,0.000009970373,0.001765319],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.5185576,"threshold_uncertainty_score":0.2857295,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01063146887899735,"score_gpt":0.2452457191532514,"score_spread":0.234614250274254,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}