{"id":"W4362466996","doi":"10.3390/cells12071059","title":"Primary Cilium Identifies a Quiescent Cell Population in the Human Intestinal Crypt","year":2023,"lang":"en","type":"article","venue":"Cells","topic":"Genetic and Kidney Cyst Diseases","field":"Biochemistry, Genetics and Molecular Biology","cited_by":7,"is_retracted":false,"has_abstract":true,"ca_institutions":"Centre Hospitalier Universitaire de Sherbrooke; Université de Sherbrooke","funders":"Canadian Institutes of Health Research; Natural Sciences and Engineering Research Council of Canada; Genentech; Turun Yliopisto","keywords":"Cilium; Biology; Crypt; Cell biology; Population; Progenitor cell; Stem cell; Paneth cell; Cell; Epithelium; Cellular differentiation; Pathology; Anatomy; Small intestine; Genetics; Endocrinology; Medicine; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00008622425,0.00007931052,0.0002249839,0.0006105676,0.0001950042,0.0002723033,0.00007540933,0.0002138596,0.001343615],"category_scores_gemma":[0.0001189401,0.00009977397,0.0001041168,0.0002611313,0.0001654815,0.00009869578,0.0001515294,0.0001303738,0.0003223867],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001155572,"about_ca_system_score_gemma":0.0001196278,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008426046,"about_ca_topic_score_gemma":0.001017755,"domain_scores_codex":[0.9999436,0.000004814141,0.000004807864,0.00001582484,0.00001725398,0.00001371908],"domain_scores_gemma":[0.9999232,0.00001504986,0.00001082532,0.000009470029,0.00001380479,0.00002760848],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000355535,0.00002439699,0.01389695,0.00003405393,0.000006024959,0.0004115118,0.00008882189,0.00002340597,0.9818282,0.0000873844,0.00004525318,0.003198528],"study_design_scores_gemma":[0.0000509533,0.0008460755,0.6175237,0.00002057838,0.00005800423,0.009714029,0.0004797709,0.00217081,0.3643596,0.0002654613,0.004491,0.00002001115],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9962418,0.00113622,0.001473596,0.00002798884,0.000005279686,0.00001521168,0.000171831,0.00004521818,0.0008828788],"genre_scores_gemma":[0.9968382,0.0003761016,0.001659304,0.00002369921,0.000007477633,0.00001387838,0.0003597214,0.000007045162,0.0007145691],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001343615,"threshold_uncertainty_score":0.004494846,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01063146887899735,"score_gpt":0.2452457191532514,"score_spread":0.234614250274254,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}