{"id":"W4362469363","doi":"10.1016/j.bbrep.2023.101461","title":"Search for lithium isotope effects in neuronal HT22 cells","year":2023,"lang":"en","type":"article","venue":"Biochemistry and Biophysics Reports","topic":"Bipolar Disorder and Treatment","field":"Medicine","cited_by":10,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Waterloo","funders":"Natural Sciences and Engineering Research Council of Canada; University of Waterloo","keywords":"Lithium (medication); Isotope; Kinetic isotope effect; Chemistry; Phosphorylation; Isotopes of lithium; Stable isotope ratio; Kinase; Radiochemistry; Biology; Biochemistry; Endocrinology; Deuterium; Physics; Organic chemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009515033,0.0001196704,0.0001703159,0.00003145568,0.00004536269,0.00001428561,0.00002188102,0.00008210891,0.000003477307],"category_scores_gemma":[0.0000150082,0.0001020233,0.00007026055,0.0001981107,0.00004441647,0.00001924549,0.00004066468,0.00009335254,0.000005321842],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001928859,"about_ca_system_score_gemma":0.00007504385,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001993048,"about_ca_topic_score_gemma":7.256979e-7,"domain_scores_codex":[0.9991801,0.000006997131,0.0001531421,0.0003142114,0.000133288,0.0002122512],"domain_scores_gemma":[0.9995944,0.00004411802,0.00002548337,0.0002034789,0.00003740828,0.00009511536],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00006314774,0.0002426731,0.05987009,0.0008269028,0.00003634878,0.0002571215,0.00006083181,0.000001180026,0.9334655,0.00001990178,0.0003935959,0.00476269],"study_design_scores_gemma":[0.000579668,0.000133722,0.05484203,0.00006107394,0.00003801772,0.00007716772,0.00002368804,0.00006812379,0.9426273,0.0001651621,0.001285023,0.00009909854],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9980305,0.0003902228,0.00001403028,0.0002700868,0.0001143594,0.0003885089,0.00001257429,0.00004720772,0.0007324647],"genre_scores_gemma":[0.9980249,0.00008629622,0.00009431443,0.00004635296,0.0001253078,0.0000620611,0.0001520312,0.00001429288,0.001394382],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.009161714,"threshold_uncertainty_score":0.416039,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01293401494194196,"score_gpt":0.2696038688311155,"score_spread":0.2566698538891736,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}