{"id":"W4362470687","doi":"10.3390/v15040906","title":"HLA Variation and SARS-CoV-2 Specific Antibody Response","year":2023,"lang":"en","type":"review","venue":"Viruses","topic":"SARS-CoV-2 and COVID-19 Research","field":"Medicine","cited_by":26,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto; Lunenfeld-Tanenbaum Research Institute; Mount Sinai Hospital","funders":"Canadian Institutes of Health Research","keywords":"Immunology; Human leukocyte antigen; Immune system; Biology; Antibody; Cytotoxic T cell; CD8; Antigen; Vaccination; Antigen presentation; T cell; Virology; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005611904,0.0002335695,0.0004483481,0.0008118581,0.00006783452,0.0005826032,0.0001816604,0.0003566735,0.00169762],"category_scores_gemma":[0.001329243,0.00009241602,0.0003227619,0.0008976177,0.0001399629,0.0004519584,0.0001797786,0.0002660456,0.0004509393],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002282987,"about_ca_system_score_gemma":0.0002370311,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004959005,"about_ca_topic_score_gemma":0.0004506007,"domain_scores_codex":[0.9996415,0.0001087798,0.00007744353,0.00008176282,0.00006772626,0.0000227365],"domain_scores_gemma":[0.9992316,0.0004281327,0.0002076166,0.00001215198,0.00009858604,0.00002191447],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0007664103,0.00007270312,0.06270459,0.01922343,0.001203481,0.001406506,0.0001599779,0.0006387638,0.007268701,0.001318257,0.01456943,0.8906679],"study_design_scores_gemma":[0.00008402682,0.001417523,0.3452723,0.01023923,0.003308631,0.02014324,0.0004146116,0.0006842126,0.008302167,0.002905816,0.6071384,0.00008989384],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.01071868,0.9863839,0.0004898324,0.0006072093,0.0002076971,0.000007002833,0.0002452108,0.000011368,0.001328968],"genre_scores_gemma":[0.06565508,0.9304783,0.0007761245,0.0005537922,0.0008169164,0.00002005361,0.0004742945,0.000005769505,0.001219635],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.00169762,"threshold_uncertainty_score":0.005679131,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.2384058336310907,"score_gpt":0.4766072632282166,"score_spread":0.2382014295971259,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}