{"id":"W4362490885","doi":"10.1158/1541-7786.c.6542164.v1","title":"Data from Notch1 Inhibition Alters the CD44&lt;sup&gt;hi&lt;/sup&gt;/CD24&lt;sup&gt;lo&lt;/sup&gt; Population and Reduces the Formation of Brain Metastases from Breast Cancer","year":2023,"lang":"en","type":"preprint","venue":"","topic":"Cancer Cells and Metastasis","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Western University","funders":"","keywords":"CD44; CD24; Population; Molecular biology; Chemistry; Internal medicine; Cancer research; Endocrinology; Medicine; Cell; Biology; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002741738,0.0006224657,0.0006667611,0.0006079893,0.0003003459,0.0005152834,0.0003747302,0.0006004251,0.01688355],"category_scores_gemma":[0.0002183565,0.0002469968,0.00066353,0.0005445628,0.0004631686,0.0005329613,0.0003073874,0.003147614,0.002867482],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003472829,"about_ca_system_score_gemma":0.0003548493,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00116029,"about_ca_topic_score_gemma":0.001602726,"domain_scores_codex":[0.9994658,0.00004934199,0.00006644175,0.0001066101,0.0001937186,0.0001181363],"domain_scores_gemma":[0.9994487,0.0001048409,0.00007138691,0.0001020279,0.00007793049,0.000195151],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00172262,0.0007020826,0.001052907,0.0002104481,0.00005781018,0.0001488683,0.00006915456,0.0001421195,0.9867166,0.0003343851,0.001930986,0.006911929],"study_design_scores_gemma":[0.0001150748,0.00107456,0.0154736,0.00001332281,0.00007315209,0.0006401198,0.0001719101,0.0006931921,0.9694648,0.0001619091,0.0121022,0.00001612871],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"dataset","genre_scores_codex":[0.9440666,0.002375977,0.007176848,0.001207941,0.0002874221,0.0001220104,0.02877151,0.0006035359,0.01538814],"genre_scores_gemma":[0.9242965,0.002519414,0.006916952,0.00113291,0.0000689692,0.0005077946,0.02524579,0.0003192987,0.03899242],"genre_candidate":"dataset","genre_consensus":null,"teacher_disagreement_score":0.01688355,"threshold_uncertainty_score":0.05648112,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0663661683027487,"score_gpt":0.3166968538861726,"score_spread":0.2503306855834239,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}