{"id":"W4362505979","doi":"10.15252/embr.202255764","title":"The mitochondrial ribosomal protein mRpL4 regulates Notch signaling","year":2023,"lang":"en","type":"article","venue":"EMBO Reports","topic":"RNA modifications and cancer","field":"Biochemistry, Genetics and Molecular Biology","cited_by":18,"is_retracted":false,"has_abstract":false,"ca_institutions":"","funders":"Institute of Genetics; National Natural Science Foundation of China","keywords":"Biology; Notch signaling pathway; Zebrafish; Cell biology; Mitochondrial ribosome; Ribosomal protein; Transcription factor; Ribosome; MT-RNR1; Mitochondrion; Genetics; Gene; Signal transduction; Mitochondrial DNA; RNA","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001522033,0.0002570807,0.000152535,0.000297106,0.0002951695,0.0006301224,0.0003138483,0.0003724844,0.001673558],"category_scores_gemma":[0.0001760906,0.0001612659,0.0001962433,0.0001487942,0.0003187137,0.0003437035,0.0003801927,0.0004736367,0.0008547714],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007589029,"about_ca_system_score_gemma":0.0002121117,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000444019,"about_ca_topic_score_gemma":0.0008246008,"domain_scores_codex":[0.999873,0.00002003048,0.000007738346,0.00002786351,0.00003659439,0.0000347214],"domain_scores_gemma":[0.9998721,0.00001591637,0.00004396242,0.00001556734,0.00002148553,0.00003096602],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001866891,0.000007707143,0.000621787,0.00002562021,0.000005903582,0.0001274734,0.00001564596,0.000129956,0.9953495,0.001015163,0.0001767518,0.002337895],"study_design_scores_gemma":[0.00001787903,0.00007642035,0.008648233,0.00000678101,0.0000145106,0.0003422712,0.00008269387,0.001926498,0.98149,0.000446393,0.006938806,0.000009603051],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9850966,0.003053668,0.004969698,0.0006598483,0.0000856948,0.00001256983,0.0004339876,0.0002628187,0.005424993],"genre_scores_gemma":[0.9952141,0.000530362,0.001172549,0.00005439433,0.00001347043,0.000006413471,0.0002646304,0.00003763497,0.002706378],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001673558,"threshold_uncertainty_score":0.005598605,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01027776562228165,"score_gpt":0.2503646116057369,"score_spread":0.2400868459834552,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}