{"id":"W4362505979","doi":"10.15252/embr.202255764","title":"The mitochondrial ribosomal protein mRpL4 regulates Notch signaling","year":2023,"lang":"en","type":"article","venue":"EMBO Reports","topic":"RNA modifications and cancer","field":"Biochemistry, Genetics and Molecular Biology","cited_by":18,"is_retracted":false,"has_abstract":false,"ca_institutions":"","funders":"Institute of Genetics; National Natural Science Foundation of China","keywords":"Biology; Notch signaling pathway; Zebrafish; Cell biology; Mitochondrial ribosome; Ribosomal protein; Transcription factor; Ribosome; MT-RNR1; Mitochondrion; Genetics; Gene; Signal transduction; Mitochondrial DNA; RNA","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002124528,0.00009433082,0.00007399229,0.00001914822,0.0002650963,0.00005844684,0.0001070003,0.00008636596,0.00001876597],"category_scores_gemma":[0.000111682,0.00006906693,0.00008083693,0.0001342985,0.00005859304,0.000002730247,0.00006492443,0.00005985989,0.00002175908],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000009318206,"about_ca_system_score_gemma":0.00008601711,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001818418,"about_ca_topic_score_gemma":0.00001187776,"domain_scores_codex":[0.999061,0.00003130239,0.0002419555,0.0002960413,0.0001506682,0.0002189916],"domain_scores_gemma":[0.9992372,0.000008790432,0.000122054,0.0005103434,0.00007484954,0.00004674806],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00001890225,0.000009357642,0.0002456326,0.000003929585,0.00002409484,0.00003296812,0.00001972019,0.0001661989,0.9875383,0.00007992538,0.009507935,0.002352986],"study_design_scores_gemma":[0.0001055665,0.00004458315,0.001594075,0.00001151162,0.000007903064,0.00005004029,0.00005020653,0.00004431615,0.7394214,0.0009879722,0.2575526,0.0001298558],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9966731,0.0004024712,0.0002101379,0.0006025169,0.0005293431,0.0002789183,0.000003139411,0.0000408741,0.001259492],"genre_scores_gemma":[0.9840862,0.00004466603,0.0002894984,0.00003678698,0.0007665583,0.0001710911,0.00008503057,0.00002052088,0.01449972],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.248117,"threshold_uncertainty_score":0.2816468,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01027776562228165,"score_gpt":0.2503646116057369,"score_spread":0.2400868459834552,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}