{"id":"W4362511688","doi":"10.1101/2023.03.30.534971","title":"Dietary calcium (Ca 2+ ) impacts Ca 2+ content and molecular expression of Ca 2+ -transporters in Malpighian tubules of the yellow fever mosquito, Aedes aegypti","year":2023,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"Neurobiology and Insect Physiology Research","field":"Neuroscience","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"McMaster University","keywords":"Malpighian tubule system; Tubule; SERCA; Internal medicine; Biology; Calcium; Endocrinology; ATPase; Kidney; Intracellular; Biochemistry; Chemistry; Enzyme; Midgut; Botany","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00005810046,0.000205269,0.0002045956,0.0001215376,0.0001278657,0.0002972043,0.00009039298,0.0002235598,0.001173818],"category_scores_gemma":[0.00008905774,0.0001944007,0.0001642403,0.00008945258,0.0001764749,0.0002201603,0.0001393789,0.0004467372,0.0001468037],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002513023,"about_ca_system_score_gemma":0.0001372116,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001535327,"about_ca_topic_score_gemma":0.002786862,"domain_scores_codex":[0.9999411,0.000007830051,0.000005177633,0.00002165739,0.00001005084,0.00001420923],"domain_scores_gemma":[0.9999011,0.00001325785,0.00003589815,0.000006457209,0.00001293981,0.00003036049],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002761873,0.000009874248,0.0009188285,0.00002071646,0.000005545859,0.00001713419,0.00001066394,0.00001499138,0.9983954,0.00001125988,0.0000243261,0.0002950124],"study_design_scores_gemma":[0.00004130268,0.000712302,0.246709,0.00001367808,0.00006770987,0.000168538,0.0002362162,0.001858656,0.7480021,0.00009517103,0.002078131,0.00001727811],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9988305,0.0002588842,0.0002189107,0.00004076758,0.000007046369,0.000006356764,0.000353926,0.00001566042,0.000267955],"genre_scores_gemma":[0.9969938,0.000266195,0.0006103218,0.0001071505,0.000005235578,0.00002631491,0.0003851436,0.00001677172,0.001589081],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001535327,"threshold_uncertainty_score":0.003926814,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04098334215956698,"score_gpt":0.2560580614600362,"score_spread":0.2150747193004693,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}