{"id":"W4362521580","doi":"10.1093/femspd/ftad005","title":"Comparative study of GBP recruitment on two cytosol-dwelling pathogens, <i>Francisella novicida</i> and <i>Shigella flexneri</i> highlights differences in GBP repertoire and in GBP1 motif requirements","year":2023,"lang":"en","type":"article","venue":"Pathogens and Disease","topic":"Immune Response and Inflammation","field":"Immunology and Microbiology","cited_by":8,"is_retracted":false,"has_abstract":true,"ca_institutions":"Dalhousie University","funders":"Fondation pour la Recherche Médicale; Agence Nationale de la Recherche; Stanford University","keywords":"Francisella; Shigella flexneri; Biology; Shigella; Francisella tularensis; Microbiology; Genetics; Bacteria; Salmonella; Virulence; Escherichia coli; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004626004,0.0002721807,0.000532494,0.0002884423,0.0001810423,0.00002530565,0.00008774661,0.00009466248,0.00001492013],"category_scores_gemma":[0.0000653653,0.0002244904,0.00004112476,0.0002855943,0.0001441322,0.00009275843,0.0001094197,0.0001417752,0.00001552831],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003032226,"about_ca_system_score_gemma":0.00005444769,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001318305,"about_ca_topic_score_gemma":0.0001473243,"domain_scores_codex":[0.9980121,0.0004840733,0.0005392937,0.0005233631,0.0001045455,0.0003366228],"domain_scores_gemma":[0.9992353,0.0002111033,0.0001556352,0.0002598572,0.00005437352,0.00008370268],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.005093738,0.00129474,0.2871819,0.000185689,0.0001436157,0.0002372277,0.01279944,0.000137466,0.6851165,0.0001769248,0.000081465,0.007551301],"study_design_scores_gemma":[0.009322727,0.001459693,0.9452665,0.0004857637,0.0001571012,0.00001172291,0.00872462,0.0007452782,0.03174082,0.0002678944,0.001175951,0.0006418603],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9946851,0.00386047,0.000003983223,0.0001214787,0.0001312718,0.0009916477,0.00008422108,0.00003196003,0.00008988904],"genre_scores_gemma":[0.9979357,0.00164633,0.0000104116,0.00005685291,0.00001368036,0.0001198535,0.00008591887,0.00001385272,0.0001174603],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.6580847,"threshold_uncertainty_score":0.9154451,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.06570622270103298,"score_gpt":0.302130722094756,"score_spread":0.236424499393723,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}