{"id":"W4362521580","doi":"10.1093/femspd/ftad005","title":"Comparative study of GBP recruitment on two cytosol-dwelling pathogens, <i>Francisella novicida</i> and <i>Shigella flexneri</i> highlights differences in GBP repertoire and in GBP1 motif requirements","year":2023,"lang":"en","type":"article","venue":"Pathogens and Disease","topic":"Immune Response and Inflammation","field":"Immunology and Microbiology","cited_by":8,"is_retracted":false,"has_abstract":true,"ca_institutions":"Dalhousie University","funders":"Fondation pour la Recherche Médicale; Agence Nationale de la Recherche; Stanford University","keywords":"Francisella; Shigella flexneri; Biology; Shigella; Francisella tularensis; Microbiology; Genetics; Bacteria; Salmonella; Virulence; Escherichia coli; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00006583513,0.0002344369,0.000184795,0.0001540349,0.0001122718,0.0001169732,0.00009460225,0.0002018167,0.000641968],"category_scores_gemma":[0.0001131195,0.00009218515,0.0001792632,0.00009598812,0.0001078903,0.0001572217,0.0001959013,0.0001641585,0.0001852992],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001102128,"about_ca_system_score_gemma":0.00007826604,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000820776,"about_ca_topic_score_gemma":0.0006602845,"domain_scores_codex":[0.9999202,0.00001076989,0.000004374991,0.00001667446,0.00001642746,0.00003149612],"domain_scores_gemma":[0.9999431,0.00001249102,0.00001114706,0.000003922117,0.00001327496,0.00001602419],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00009682383,0.000004212667,0.0007252621,0.00002623723,0.000002781646,0.00002659498,0.00001766917,0.00002607952,0.9983689,0.00001246122,0.00001353965,0.0006793888],"study_design_scores_gemma":[0.000007959836,0.0003750878,0.1043999,0.00001369635,0.00002472253,0.0006059319,0.0002021119,0.001502204,0.8911522,0.00004839872,0.001656969,0.00001087997],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.998836,0.0003039963,0.0003692964,0.00001528568,0.000002665343,0.000003930078,0.0001056093,0.000008145713,0.000355221],"genre_scores_gemma":[0.9976947,0.0003300917,0.000746829,0.00003251512,0.000003359431,0.00001597013,0.000412888,0.000007904339,0.0007557574],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.000820776,"threshold_uncertainty_score":0.002147615,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.06570622270103298,"score_gpt":0.302130722094756,"score_spread":0.236424499393723,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}