{"id":"W4362522579","doi":"10.1111/febs.16779","title":"N‐glycosylation mediated folding and quality control in serine proteases of the hepsin family","year":2023,"lang":"en","type":"article","venue":"FEBS Journal","topic":"Glycosylation and Glycoproteins Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":5,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University; McGill University Health Centre","funders":"","keywords":"Proteases; Serine; Folding (DSP implementation); Glycosylation; Chemistry; Quality (philosophy); Biochemistry; Computational biology; Biology; Enzyme; Engineering; Physics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0008227788,0.00006469204,0.0001033751,0.00008090854,0.00007948349,0.00002350667,0.000104093,0.00006488135,0.000017209],"category_scores_gemma":[0.0006566087,0.00004611534,0.00004612788,0.0002349757,0.00004689631,0.000006280746,0.00006112606,0.0001417643,0.000003395651],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001208704,"about_ca_system_score_gemma":0.00007849038,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00006801241,"about_ca_topic_score_gemma":0.00009277067,"domain_scores_codex":[0.9990578,0.0002156751,0.0002473764,0.0001087476,0.0002151715,0.000155258],"domain_scores_gemma":[0.9995826,0.00003428816,0.0001099828,0.00011896,0.0001004087,0.00005372397],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.000175964,0.00002762146,0.08076713,0.00002095493,0.00001690346,0.000003389989,0.00004421956,0.000164527,0.9158331,0.00003352702,0.0002341101,0.002678549],"study_design_scores_gemma":[0.00222627,0.0001752053,0.9306176,0.00005498081,0.000004551817,0.00002446788,0.0001381889,0.001747003,0.05918783,0.0002187139,0.005502291,0.0001028633],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9983202,0.0002866222,0.0003600029,0.0005808053,0.00006690972,0.0002454756,0.00001544596,0.000004812983,0.0001197672],"genre_scores_gemma":[0.9993938,0.0001835229,0.00004691847,0.00007738127,0.00007418241,0.00001076222,0.00001218096,0.000007242217,0.0001940536],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.8566453,"threshold_uncertainty_score":0.1880529,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03142836662738085,"score_gpt":0.3151918394960787,"score_spread":0.2837634728686979,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}