{"id":"W4362523523","doi":"10.1093/oncolo/oyad073","title":"Development and Validation of a Prognostic Risk Model for Patients with Advanced Melanoma Treated with Immune Checkpoint Inhibitors","year":2023,"lang":"en","type":"article","venue":"The Oncologist","topic":"Cancer Immunotherapy and Biomarkers","field":"Medicine","cited_by":14,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Calgary","funders":"","keywords":"Medicine; Internal medicine; Lactate dehydrogenase; Proportional hazards model; Oncology; Melanoma; Cohort; Retrospective cohort study; White blood cell; Cancer research","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.003993535,0.000765483,0.0006011929,0.0008671482,0.0003142489,0.0009394219,0.0005494033,0.0003822373,0.0007281986],"category_scores_gemma":[0.006431791,0.0002203362,0.00111471,0.0003469898,0.000208512,0.0002473751,0.0005192881,0.0008845389,0.0002371948],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007206959,"about_ca_system_score_gemma":0.001317795,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.003167441,"about_ca_topic_score_gemma":0.002503949,"domain_scores_codex":[0.9992812,0.0003843709,0.00005175774,0.0001249265,0.00008940045,0.00006841697],"domain_scores_gemma":[0.9964917,0.002413085,0.0005079139,0.0001519743,0.0002877949,0.0001473826],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"simulation_or_modeling","study_design_scores_codex":[0.001072389,0.0004073426,0.7733851,0.00007076906,0.0005785559,0.0002673397,0.0001450455,0.1768416,0.001538254,0.0004203223,0.002180197,0.04309311],"study_design_scores_gemma":[0.00007303142,0.0003049838,0.05738759,0.00003335071,0.0001780408,0.0002030075,0.00004871706,0.9395791,0.0007413917,0.000802839,0.0006308633,0.00001719305],"study_design_candidate":"simulation_or_modeling","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9292577,0.0003215739,0.06744876,0.0007517026,0.00004351564,0.0001158747,0.001155655,0.0002789269,0.0006261667],"genre_scores_gemma":[0.9881284,0.00006040917,0.01040959,0.00004755282,0.00002215367,0.00006985354,0.001100539,0.00001343791,0.0001480336],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003993535,"threshold_uncertainty_score":0.02112013,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02007059454415651,"score_gpt":0.2679739571272112,"score_spread":0.2479033625830547,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}