{"id":"W4362541216","doi":"10.1158/1538-7445.am2023-2993","title":"Abstract 2993: Unmutated tumor antigens are abundant and contribute to tumor control in melanoma","year":2023,"lang":"en","type":"article","venue":"Cancer Research","topic":"Immunotherapy and Immune Responses","field":"Immunology and Microbiology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Montréal","funders":"","keywords":"Melanoma; Antigen; Cancer research; Immune checkpoint; Biology; Immunotherapy; Major histocompatibility complex; Tumor antigen; Immune system; Immunology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00008979366,0.000187945,0.0001983369,0.0003618045,0.0001232504,0.0002806567,0.00008837789,0.00017696,0.003471865],"category_scores_gemma":[0.0001560893,0.00005489676,0.0001298559,0.0002546898,0.0000954413,0.0001149818,0.0001502427,0.0002040221,0.0007040942],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001130524,"about_ca_system_score_gemma":0.00007197115,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002329121,"about_ca_topic_score_gemma":0.0001787077,"domain_scores_codex":[0.9998951,0.00001313635,0.00001046025,0.00002641898,0.00003413983,0.0000207524],"domain_scores_gemma":[0.9998767,0.00001718786,0.00004618752,0.000009098194,0.00001895697,0.00003188734],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.0003657353,0.0000381022,0.0212238,0.0000872446,0.00002098744,0.0002250251,0.00003334855,0.00006515937,0.9713553,0.00005621107,0.0001566593,0.006372578],"study_design_scores_gemma":[0.00002497048,0.0008228474,0.7561957,0.00003509834,0.00009137637,0.006068471,0.0001922362,0.001356499,0.2289352,0.0002935463,0.005972773,0.00001117108],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9974395,0.001015574,0.0002935829,0.00002741815,0.000009380638,0.000006022481,0.0004324586,0.00001666601,0.0007593776],"genre_scores_gemma":[0.9981718,0.0002515256,0.0002867693,0.00002113314,0.00001453988,0.000004922628,0.0005504914,0.00001017062,0.0006887033],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003471865,"threshold_uncertainty_score":0.0116145,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03907128213056634,"score_gpt":0.3571037906141813,"score_spread":0.318032508483615,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}