{"id":"W4362544072","doi":"10.1158/1538-7445.am2023-2516","title":"Abstract 2516: Analysis of CLL Celllular Environment and Response (ACCER) is a novel method to understand the microenvironment in CLL","year":2023,"lang":"en","type":"article","venue":"Cancer Research","topic":"Chronic Lymphocytic Leukemia Research","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Manitoba; University of Alberta","funders":"","keywords":"Chronic lymphocytic leukemia; Tumor microenvironment; Stromal cell; Ibrutinib; Cancer research; Cell culture; Bone marrow; Fludarabine; Medicine; Leukemia; Chemistry; Immunology; Biology; Internal medicine; Chemotherapy; Tumor cells; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000437333,0.0004683665,0.0003382936,0.001599578,0.0004886152,0.0005734868,0.0002501827,0.0006461322,0.01216094],"category_scores_gemma":[0.000267788,0.0002816251,0.0002935155,0.0005939023,0.0002281882,0.0004584519,0.0004380746,0.0009338421,0.003071064],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003533631,"about_ca_system_score_gemma":0.000276809,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001088569,"about_ca_topic_score_gemma":0.00279697,"domain_scores_codex":[0.999519,0.00007431464,0.00003190555,0.0000952753,0.0002216853,0.00005777636],"domain_scores_gemma":[0.999759,0.00005267183,0.00004875615,0.00002819137,0.00007051975,0.00004086055],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001420893,0.00003872129,0.001059518,0.00008040449,0.000008383728,0.0001349686,0.00004838454,0.00005765715,0.986134,0.000258777,0.001303172,0.01073386],"study_design_scores_gemma":[0.00003799754,0.0004025597,0.04777658,0.0000315322,0.0000509486,0.00176321,0.0002176281,0.002724158,0.9044514,0.000358848,0.04214032,0.0000448051],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.7240841,0.01417261,0.1879363,0.002020528,0.001253398,0.0009697537,0.006722341,0.006226893,0.05661403],"genre_scores_gemma":[0.6706604,0.005376967,0.206482,0.001117773,0.0003546328,0.001117602,0.005512315,0.0008310723,0.1085473],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01216094,"threshold_uncertainty_score":0.04068238,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1416326396447894,"score_gpt":0.4527055141488983,"score_spread":0.3110728745041088,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}