{"id":"W4362544124","doi":"10.1158/1538-7445.am2023-2274","title":"Abstract 2274: An immune-educating therapy, Maveropepimut-S, elicits a diverse and active anti-tumor T cell response in patients with advanced recurrent ovarian cancer","year":2023,"lang":"en","type":"article","venue":"Cancer Research","topic":"Monoclonal and Polyclonal Antibodies Research","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"MEG-3 (Canada); Nova Scotia Hospital","funders":"","keywords":"Survivin; Immunotherapy; T cell; Immune system; Immunology; T-cell receptor; Cancer research; Medicine; Epitope; Ovarian cancer; Antigen; Population; Cancer; Biology; Internal medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001176971,0.0001402257,0.0003287854,0.0001032883,0.0001052543,0.0002064548,0.00008186521,0.000170653,0.001167776],"category_scores_gemma":[0.0002027803,0.00007588435,0.0001298182,0.00007665507,0.00007954911,0.00008134368,0.00009325738,0.0002614123,0.0002630095],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001741944,"about_ca_system_score_gemma":0.0001783371,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004010465,"about_ca_topic_score_gemma":0.0006800178,"domain_scores_codex":[0.9999484,0.00001381293,0.000003627938,0.00000749122,0.00000924908,0.00001744853],"domain_scores_gemma":[0.9999514,0.00001140384,0.000008816769,0.000004575131,0.000004820426,0.00001906865],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","study_design_scores_codex":[0.02205216,0.003496322,0.07964887,0.0003557313,0.000150096,0.002253316,0.0006028597,0.001393047,0.6785349,0.0001402657,0.002837473,0.2085349],"study_design_scores_gemma":[0.00535413,0.207134,0.5363783,0.0000680138,0.0004987905,0.01533158,0.0004473389,0.00641832,0.2031361,0.0002785203,0.02491402,0.00004092342],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"other","genre_scores_codex":[0.9991091,0.0002542846,0.00005456572,0.00002949785,0.00000456939,0.00001834126,0.00004232705,0.00001001744,0.0004772427],"genre_scores_gemma":[0.9992174,0.00009281257,0.00007627074,0.00004739752,0.000009451222,0.00001513122,0.0001372377,0.000002824192,0.0004015467],"genre_candidate":"other","genre_consensus":null,"teacher_disagreement_score":0.001167776,"threshold_uncertainty_score":0.003906608,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0733019451402827,"score_gpt":0.4208981716045319,"score_spread":0.3475962264642491,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}