{"id":"W4362575034","doi":"10.1002/pdi.2448","title":"Teplizumab – preventative approaches to type 1 diabetes mellitus","year":2023,"lang":"en","type":"article","venue":"Practical Diabetes","topic":"Diabetes and associated disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":5,"is_retracted":false,"has_abstract":true,"ca_institutions":"Saskatchewan Health; Saskatchewan Health Authority","funders":"","keywords":"Medicine; Type 1 diabetes; Diabetes mellitus; Pancreas; Artificial pancreas; Insulin; Intensive care medicine; Immune system; Immunology; Internal medicine; Endocrinology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0003613054,0.0002156319,0.0002233704,0.00007762613,0.0001077889,0.00007719893,0.0001844756,0.0001588982,0.00007836739],"category_scores_gemma":[0.00135934,0.0002017379,0.0001087047,0.0005355533,0.00007546353,0.00001483932,0.0002332635,0.0001363597,0.0007857763],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001719344,"about_ca_system_score_gemma":0.00006772516,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000002179911,"about_ca_topic_score_gemma":0.000002955853,"domain_scores_codex":[0.99827,0.0001318028,0.0002079965,0.0004998295,0.0002096026,0.000680806],"domain_scores_gemma":[0.9991716,0.0001674261,0.00007242194,0.0003078849,0.00006545848,0.0002152785],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002295859,0.001528373,0.1722833,0.0002831117,0.002118558,0.00001494366,0.0005888011,0.0006513026,0.4201686,0.006006242,0.2805563,0.1155709],"study_design_scores_gemma":[0.001839248,0.002791753,0.06124309,0.0001025662,0.0002998439,8.480061e-7,0.001401244,0.001985216,0.5166348,0.007884746,0.4038789,0.001937755],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9913068,0.0007524487,0.0000358216,0.003155452,0.0001984636,0.0003246432,0.00003716324,0.00009694853,0.004092299],"genre_scores_gemma":[0.9959846,0.0001982939,0.00101795,0.001013847,0.0001639931,0.0001195414,0.0003372893,0.00005013057,0.001114378],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1233226,"threshold_uncertainty_score":0.9999923,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05886904840996309,"score_gpt":0.298603818847544,"score_spread":0.2397347704375809,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}