{"id":"W4362578693","doi":"10.1016/j.jaad.2023.03.035","title":"Malignancy rates through 5 years of follow-up in patients with moderate-to-severe psoriasis treated with guselkumab: Pooled results from the VOYAGE 1 and VOYAGE 2 trials","year":2023,"lang":"en","type":"article","venue":"Journal of the American Academy of Dermatology","topic":"Psoriasis: Treatment and Pathogenesis","field":"Immunology and Microbiology","cited_by":19,"is_retracted":false,"has_abstract":true,"ca_institutions":"Probity Medical Research; Dalhousie University","funders":"Janssen Research and Development; LEO Pharma; Sun Pharma; Argenx; Janssen Scientific Affairs; Amgen; Pfizer; Celgene; AstraZeneca; Eli Lilly and Company; Bristol-Myers Squibb","keywords":"Medicine; Malignancy; Psoriasis; Skin cancer; Population; Dermatology; Incidence (geometry); Epidemiology; Cancer registry; Basal cell carcinoma; Cancer; Surgery; Internal medicine; Basal cell","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.007992084,0.0008199528,0.002739292,0.00149779,0.0002546495,0.001368529,0.0006046705,0.0008185492,0.001185715],"category_scores_gemma":[0.008304426,0.0005171928,0.00935126,0.001293918,0.0003721041,0.000751441,0.0007771845,0.000851276,0.0001075182],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004018387,"about_ca_system_score_gemma":0.0003603169,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001432588,"about_ca_topic_score_gemma":0.003048674,"domain_scores_codex":[0.9950278,0.002764362,0.0006962187,0.0008376121,0.0004722849,0.0002017445],"domain_scores_gemma":[0.9926559,0.003284211,0.002828836,0.0006236791,0.0003291407,0.0002783064],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"meta_analysis","study_design_scores_codex":[0.1936236,0.0002698013,0.4664535,0.009403569,0.2558817,0.0001751613,0.0002524087,0.002088349,0.001779292,0.0001720085,0.002205529,0.06769505],"study_design_scores_gemma":[0.02173709,0.00898181,0.7625829,0.00137857,0.1980211,0.0006261565,0.0001937541,0.001106779,0.0008653775,0.0003853753,0.004018774,0.0001022479],"study_design_candidate":"meta_analysis","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.7608013,0.232474,0.001006703,0.0002559736,0.0002312222,0.0002876386,0.003223191,0.00005596362,0.001664021],"genre_scores_gemma":[0.9827308,0.01441032,0.0003315663,0.0002062576,0.0002011178,0.0001708649,0.001690147,0.00001301646,0.0002459552],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.007992084,"threshold_uncertainty_score":0.04226673,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02426202697678935,"score_gpt":0.2723675207592076,"score_spread":0.2481054937824182,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}