{"id":"W4362587450","doi":"10.3389/fimmu.2023.1106652","title":"Distinct subpopulations of DN1 thymocytes exhibit preferential γδ T lineage potential","year":2023,"lang":"en","type":"article","venue":"Frontiers in Immunology","topic":"T-cell and B-cell Immunology","field":"Immunology and Microbiology","cited_by":15,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Cancer Council Victoria; National Health and Medical Research Council; Medical Research Council; St Vincent's Hospital Melbourne; University of Toronto; Diabetes Australia; U.S. Department of Defense","keywords":"Biology; Thymocyte; T cell; CD8; Cell biology; Immune system; Progenitor cell; Transcription factor; Cellular differentiation; Immunology; Stem cell; Genetics; Gene","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001156068,0.0003396393,0.0002106467,0.0004176369,0.000222325,0.0003634063,0.0001733014,0.0001776515,0.002057208],"category_scores_gemma":[0.0001550376,0.0001412748,0.0001946479,0.0001522596,0.0001205089,0.0001876666,0.0002649927,0.000634023,0.0006430856],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001954407,"about_ca_system_score_gemma":0.0001532307,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003881401,"about_ca_topic_score_gemma":0.0009963941,"domain_scores_codex":[0.999861,0.000008142026,0.00001211149,0.00005566231,0.00002706023,0.00003598977],"domain_scores_gemma":[0.9998127,0.000028895,0.00004978093,0.00002022735,0.00002799238,0.00006039237],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00007015755,0.000009872051,0.00257295,0.00003337221,0.000002713442,0.0000572791,0.00004810816,0.00002851472,0.9953301,0.00008135911,0.00002341217,0.001742173],"study_design_scores_gemma":[0.00001493502,0.0002414308,0.1207729,0.00003266925,0.00003990077,0.001761861,0.000233627,0.000709962,0.8691212,0.0002236342,0.006834404,0.00001349887],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9921833,0.001122075,0.002883939,0.00003063155,0.00001109205,0.0000344409,0.0007556619,0.0000517281,0.002927171],"genre_scores_gemma":[0.9882511,0.0009280117,0.003278595,0.0001237582,0.00001457339,0.00005923794,0.001645798,0.00005970841,0.005639187],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002057208,"threshold_uncertainty_score":0.006882012,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01206589440037438,"score_gpt":0.223921559060477,"score_spread":0.2118556646601027,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}