{"id":"W4362588164","doi":"10.1016/j.jchf.2023.01.027","title":"Event Adjudication Is Unnecessary in Blinded Trials and May Be Detrimental","year":2023,"lang":"en","type":"letter","venue":"JACC Heart Failure","topic":"Cardiovascular Function and Risk Factors","field":"Medicine","cited_by":4,"is_retracted":false,"has_abstract":false,"ca_institutions":"Population Health Research Institute","funders":"","keywords":"Medicine; Heart failure; Renal function; Ejection fraction; Cardiology; Internal medicine; Proportional hazards model; Heart failure with preserved ejection fraction; Creatinine; Stroke volume; Diastole; Blood pressure","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.001380495,0.0003287677,0.001293797,0.0006659304,0.00006752453,0.00004346122,0.00006924507,0.001127826,0.0006875708],"category_scores_gemma":[0.0003697767,0.0002685092,0.0006823823,0.0005232239,0.00005874052,0.00006759675,0.00006782942,0.001581753,0.0002610646],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00018974,"about_ca_system_score_gemma":0.0002247507,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003662211,"about_ca_topic_score_gemma":0.00006149842,"domain_scores_codex":[0.9972075,0.0004097333,0.0006946469,0.0006083968,0.00073447,0.000345223],"domain_scores_gemma":[0.9987925,0.0003207076,0.0001636419,0.0005251201,0.00006759677,0.0001304032],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00006858286,0.00003286898,0.01187466,0.0001863084,0.0003329049,0.0001503359,0.0001111901,6.817452e-7,0.0002239715,0.000001047735,0.9859049,0.001112534],"study_design_scores_gemma":[0.00282186,0.00009163356,0.04025627,0.0002710653,0.0003787474,0.0001360253,0.0001566702,0.00001079228,0.0005493311,0.00001549665,0.9550637,0.0002483859],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"commentary","genre_gemma":"commentary","genre_scores_codex":[0.02211285,0.0009530003,0.00001866117,0.9741877,0.00100861,0.001349438,0.0001206912,0.0001445032,0.0001045968],"genre_scores_gemma":[0.04516857,0.001533093,0.0005546741,0.9278844,0.009097788,0.000258333,0.003071056,0.0002475933,0.01218452],"genre_candidate":"commentary","genre_consensus":"commentary","teacher_disagreement_score":0.04630327,"threshold_uncertainty_score":0.9999767,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.06474600022100042,"score_gpt":0.3430725553948408,"score_spread":0.2783265551738404,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}