{"id":"W4362588164","doi":"10.1016/j.jchf.2023.01.027","title":"Event Adjudication Is Unnecessary in Blinded Trials and May Be Detrimental","year":2023,"lang":"en","type":"letter","venue":"JACC Heart Failure","topic":"Cardiovascular Function and Risk Factors","field":"Medicine","cited_by":4,"is_retracted":false,"has_abstract":false,"ca_institutions":"Population Health Research Institute","funders":"","keywords":"Medicine; Heart failure; Renal function; Ejection fraction; Cardiology; Internal medicine; Proportional hazards model; Heart failure with preserved ejection fraction; Creatinine; Stroke volume; Diastole; Blood pressure","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":["metaresearch"],"consensus_categories":[],"category_scores_codex":[0.1246208,0.001083897,0.003524527,0.002099882,0.004205423,0.0085578,0.003426502,0.07038093,0.01024561],"category_scores_gemma":[0.4176555,0.001449743,0.003198249,0.001801668,0.007579336,0.005211684,0.002661902,0.03677002,0.01406545],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.004761886,"about_ca_system_score_gemma":0.007376031,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001970315,"about_ca_topic_score_gemma":0.005805011,"domain_scores_codex":[0.835969,0.1079551,0.02039768,0.00670034,0.02558676,0.003391113],"domain_scores_gemma":[0.5086081,0.4092048,0.02383477,0.01662226,0.0298593,0.01187078],"domain_codex":null,"domain_gemma":"methods","domain_candidate":"methods","domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0009582769,0.0001073088,0.002011704,0.0004713625,0.0003331538,0.001836716,0.0003083909,0.0002104203,0.0002723802,0.01324898,0.9349099,0.04533141],"study_design_scores_gemma":[0.004138583,0.000838636,0.005866906,0.002852818,0.0005490385,0.003771045,0.0004325182,0.003211437,0.0006479686,0.110829,0.8665902,0.0002717015],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"commentary","genre_gemma":"commentary","genre_scores_codex":[0.0008485343,0.001813825,0.002059594,0.9499701,0.03340889,0.0002091257,0.0001730475,0.0001295632,0.01138747],"genre_scores_gemma":[0.006247931,0.0006425421,0.002558662,0.9274999,0.0588993,0.0002982456,0.00005911085,0.00005931675,0.003734972],"genre_candidate":"commentary","genre_consensus":"commentary","teacher_disagreement_score":0.8753791,"threshold_uncertainty_score":0.6590659,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.06474600022100042,"score_gpt":0.3430725553948408,"score_spread":0.2783265551738404,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}