{"id":"W4362592058","doi":"10.1158/1538-7445.am2023-5142","title":"Abstract 5142: 50-parameter flow cytometry by CyTOF empowers comprehensive single-cell immune profiling of pulmonary immunosenescence in aged mice","year":2023,"lang":"en","type":"article","venue":"Cancer Research","topic":"Single-cell and spatial transcriptomics","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Integrity Testing Laboratory (Canada)","funders":"","keywords":"Immunosenescence; Mass cytometry; Flow cytometry; Immune system; Immunology; Biology; Antibody; Phenotype; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005842655,0.0002147582,0.0003104589,0.0003003296,0.0001118906,0.00003736819,0.0005183603,0.0002502245,0.00003393197],"category_scores_gemma":[0.0001088017,0.0002227435,0.0001324485,0.0008691178,0.0003199327,0.00001265121,0.0001899611,0.0005353794,0.00002024202],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00009579166,"about_ca_system_score_gemma":0.0002009167,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008097093,"about_ca_topic_score_gemma":0.00004263544,"domain_scores_codex":[0.9976682,0.0001805006,0.0004465014,0.0005625651,0.0004549192,0.0006873295],"domain_scores_gemma":[0.9989054,0.0001725324,0.00009078064,0.0004642583,0.0002662605,0.0001007745],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0005667402,0.0002413668,0.004998933,0.0002769199,0.00003717616,0.00003504572,0.0001350178,0.0002848646,0.9905105,4.131101e-7,0.0004692852,0.002443711],"study_design_scores_gemma":[0.0007306695,0.0001759964,0.009906851,0.000131718,0.000004530998,0.000003286865,0.0005285568,0.0002916995,0.9868778,0.00001033768,0.001104833,0.0002337128],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9922032,0.006391523,0.00007832392,0.00008348424,0.0002417226,0.000432843,0.0001342914,0.00002165146,0.0004129783],"genre_scores_gemma":[0.9965892,0.002073457,0.0002786298,0.00004078992,0.00008274107,0.00007397401,0.0003095793,0.00005474203,0.0004968717],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004907918,"threshold_uncertainty_score":0.9083218,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05775244397403355,"score_gpt":0.3377831415835639,"score_spread":0.2800306976095303,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}