{"id":"W4362593389","doi":"10.1158/1538-7445.am2023-4011","title":"Abstract 4011: Preferential cytotoxicity of ESK981 in neuroendocrine prostate cancer","year":2023,"lang":"en","type":"article","venue":"Cancer Research","topic":"Prostate Cancer Treatment and Research","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"","keywords":"Prostate cancer; Medicine; Cancer; Cancer research; Population; Prostate; Apoptosis; Pathology; Internal medicine; Biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009837191,0.000331219,0.0002560508,0.0001941467,0.0001236541,0.0002556388,0.0001878458,0.000276313,0.002756246],"category_scores_gemma":[0.0000819698,0.00008745729,0.0001826532,0.0002145665,0.0001319286,0.0001875326,0.0001500258,0.0006108254,0.0007602068],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002205393,"about_ca_system_score_gemma":0.0002381904,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004305002,"about_ca_topic_score_gemma":0.0005991663,"domain_scores_codex":[0.9999149,0.000009895455,0.00001153237,0.00001742855,0.00002840558,0.00001780324],"domain_scores_gemma":[0.9999299,0.00001547384,0.00001323476,0.000009584967,0.00001195492,0.00001988251],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0004549847,0.0001326166,0.0006617899,0.0001163076,0.00001039652,0.0001033317,0.00001421455,0.0001767421,0.9925417,0.00008989297,0.0003568669,0.005341212],"study_design_scores_gemma":[0.00004175849,0.001436585,0.004310515,0.00000885255,0.0000184472,0.0006244347,0.00001796644,0.0005123381,0.9902374,0.00004527022,0.002741641,0.00000479081],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9890387,0.00312185,0.001736147,0.0002003369,0.00007332337,0.00005060082,0.001691707,0.0001593879,0.003927938],"genre_scores_gemma":[0.990388,0.001528111,0.0009982077,0.00006967822,0.00001640042,0.00004269268,0.002137794,0.00001849061,0.004800591],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002756246,"threshold_uncertainty_score":0.009220541,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1377556252055585,"score_gpt":0.4605672393863665,"score_spread":0.322811614180808,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}