{"id":"W4362594355","doi":"10.1158/1538-7445.am2023-5596","title":"Abstract 5596: Cell free DNA levels and fragmentation patterns in different liquid biopsy analytes (blood, urine and vaginal fluid) in cervical cancer patients","year":2023,"lang":"en","type":"article","venue":"Cancer Research","topic":"Cancer Genomics and Diagnostics","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University Health Centre","funders":"","keywords":"Liquid biopsy; Biopsy; Medicine; Cervical cancer; Urine; Cancer; Cell-free fetal DNA; Intraepithelial neoplasia; Cervical intraepithelial neoplasia; DNA fragmentation; Field cancerization; Dysplasia; Internal medicine; Pathology; Oncology; Apoptosis; Biology; Programmed cell death; Prostate cancer","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001963985,0.0002344866,0.0002278918,0.001127746,0.0003492699,0.0005401838,0.0002046208,0.000425165,0.002480773],"category_scores_gemma":[0.001088925,0.0001261105,0.0001368665,0.0006610136,0.0002675297,0.0002427579,0.0002721754,0.0002665173,0.0003291436],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005486993,"about_ca_system_score_gemma":0.0002202054,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.003885632,"about_ca_topic_score_gemma":0.003269862,"domain_scores_codex":[0.9997752,0.00002952521,0.00002972022,0.00006211428,0.00004959034,0.00005386987],"domain_scores_gemma":[0.9995152,0.0001107758,0.0001305213,0.00001947433,0.0001000399,0.0001239701],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0008517602,0.00004179441,0.9761649,0.0000708794,0.00003995039,0.0005580421,0.00024322,0.00005266295,0.01623507,0.00002179955,0.0003050528,0.005414861],"study_design_scores_gemma":[0.00001174499,0.0004243834,0.9930628,0.00001584807,0.00003195041,0.001774034,0.0003324524,0.0001466913,0.003726449,0.00002020633,0.0004453752,0.000008152223],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9983447,0.0005545372,0.00008515579,0.00003345155,0.000006947042,0.0000123045,0.0005325245,0.00001023172,0.000420242],"genre_scores_gemma":[0.9990903,0.00006986209,0.0001324275,0.00004103066,0.000004941336,0.0000104962,0.0003877417,0.000002756343,0.0002605662],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003885632,"threshold_uncertainty_score":0.008298993,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03380923435283535,"score_gpt":0.3418572858748089,"score_spread":0.3080480515219736,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}