{"id":"W4362594585","doi":"10.1002/alz.13056","title":"Hippocampal metabolic subregions and networks: Behavioral, molecular, and pathological aging profiles","year":2023,"lang":"en","type":"article","venue":"Alzheimer s & Dementia","topic":"Memory and Neural Mechanisms","field":"Neuroscience","cited_by":11,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Johnson and Johnson Pharmaceutical Research and Development; National Institute of Mental Health; National Institute on Aging; National Institute of Biomedical Imaging and Bioengineering; Canadian Institutes of Health Research; National Institutes of Health; H. Lundbeck A/S; Servier; Eisai; Heinrich-Heine-Universität Düsseldorf; Genentech; IXICO; Deutsche Forschungsgemeinschaft; Helmholtz-Gemeinschaft; Northern California Institute for Research and Education; University of Southern California; Pfizer; Biogen; BioClinica; Janssen Alzheimer Immunotherapy Research And Development; European Commission; Eli Lilly and Company; U.S. Department of Defense; Meso Scale Diagnostics; Alzheimer's Disease Neuroimaging Initiative; Novartis Pharmaceuticals Corporation; Bristol-Myers Squibb; Alzheimer's Association; Foundation for the National Institutes of Health","keywords":"Subiculum; Hippocampal formation; Neuroscience; Hippocampus; Pathological; Biology; Psychology; Medicine; Pathology; Dentate gyrus","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001421376,0.0002209292,0.000196949,0.0004990553,0.0001509417,0.0002826405,0.0001108785,0.0001211244,0.0009434485],"category_scores_gemma":[0.0002325879,0.00008448574,0.0001079048,0.0003309355,0.0001946271,0.0002832262,0.0002588116,0.0001220597,0.0001066179],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000184232,"about_ca_system_score_gemma":0.0001390066,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001821396,"about_ca_topic_score_gemma":0.003878827,"domain_scores_codex":[0.9999689,0.000004025867,0.000002657281,0.00001292139,0.000005449139,0.000006068342],"domain_scores_gemma":[0.999893,0.00001001958,0.00005327861,0.00001023923,0.00001564526,0.00001790406],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.00245871,0.0001086966,0.7956967,0.0002238134,0.0003332314,0.0004307906,0.0007388818,0.0007066696,0.1537499,0.0006738325,0.0004823558,0.04439631],"study_design_scores_gemma":[0.000004835245,0.0001177565,0.994532,0.000007713382,0.00003964812,0.0005036948,0.0001796775,0.0002820879,0.003447507,0.00058667,0.0002934907,0.000004828338],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9974586,0.0008351454,0.0005650205,0.00003008861,0.000002687642,0.000009439608,0.000492141,0.00001187096,0.0005948363],"genre_scores_gemma":[0.9985496,0.0002959555,0.0005002568,0.00001081802,0.000002706937,0.0000100233,0.0003092307,0.00000284043,0.0003185445],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001821396,"threshold_uncertainty_score":0.003621578,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1154562506317816,"score_gpt":0.3325733376814525,"score_spread":0.2171170870496709,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}