{"id":"W4362602907","doi":"10.21203/rs.3.rs-2747693/v1","title":"IL-4 induces CD22 expression to restrain the effector program of self-reactive virtual memory T cells","year":2023,"lang":"en","type":"preprint","venue":"Research Square","topic":"Immune Cell Function and Interaction","field":"Immunology and Microbiology","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"McGill University Health Centre; McGill University","funders":"","keywords":"Effector; CD22; Cell biology; Expression (computer science); Chemistry; Computer science; Biology; Programming language; Immunology; Immunohistochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001692372,0.0004777612,0.0003173469,0.0003082863,0.0002001829,0.0005554089,0.0002442316,0.0002729599,0.0044215],"category_scores_gemma":[0.0002022252,0.0002024133,0.0003420886,0.0001363025,0.0002414615,0.0002148146,0.0003673279,0.001205291,0.001091775],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002614784,"about_ca_system_score_gemma":0.000214034,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002767293,"about_ca_topic_score_gemma":0.0004936043,"domain_scores_codex":[0.9997912,0.00003496201,0.000009482162,0.00003047981,0.00002996877,0.0001039213],"domain_scores_gemma":[0.9998716,0.00002491327,0.00002013052,0.00002501751,0.00001429765,0.00004403399],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002497735,0.00007563039,0.0003042889,0.00002461068,0.000007042032,0.0000794822,0.00001473478,0.0001170686,0.9965911,0.0001849979,0.0001468622,0.002204499],"study_design_scores_gemma":[0.00009233662,0.0004793032,0.009863848,0.00001190132,0.0000363434,0.0003139833,0.00007211264,0.001758394,0.9823506,0.0004927948,0.004521445,0.000007054512],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9926693,0.0008521742,0.002421479,0.0001486495,0.00009089233,0.00002271578,0.0001311705,0.000114814,0.003548815],"genre_scores_gemma":[0.9926483,0.0002569369,0.0008157684,0.0001054805,0.00004725326,0.00002484019,0.0002455176,0.00006273654,0.005793082],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0044215,"threshold_uncertainty_score":0.01479137,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05421366928978086,"score_gpt":0.3736827524651053,"score_spread":0.3194690831753244,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}