{"id":"W4362635299","doi":"10.1101/2023.04.03.535419","title":"Effects of VCD-induced ovarian failure on single muscle fiber contractility in a mouse model of menopause","year":2023,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"Muscle Physiology and Disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":true,"ca_institutions":"Dalhousie University; University of Guelph","funders":"","keywords":"Contractility; Ovariectomized rat; Menopause; Internal medicine; Endocrinology; Medicine; Soleus muscle; Chemistry; Cardiology; Skeletal muscle; Estrogen","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004612681,0.0005139469,0.0005257038,0.001089381,0.0002289605,0.0003896291,0.0003787009,0.0006960781,0.001567763],"category_scores_gemma":[0.0002834593,0.0003480596,0.0005359412,0.0003018352,0.0006112666,0.0003230023,0.0003179686,0.001035343,0.0002550937],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004718987,"about_ca_system_score_gemma":0.0003068761,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007042428,"about_ca_topic_score_gemma":0.0009987487,"domain_scores_codex":[0.9996551,0.00004719793,0.00003574394,0.00008655468,0.00009184395,0.00008348965],"domain_scores_gemma":[0.9994757,0.00006502817,0.0001946442,0.00006034829,0.00003811764,0.0001661487],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00202907,0.0005048759,0.001776231,0.0001057177,0.00002576658,0.0003028464,0.00004890952,0.000179891,0.9919802,0.000165608,0.0001984199,0.002682409],"study_design_scores_gemma":[0.001139929,0.01909285,0.0688175,0.0001457778,0.0001728254,0.002332255,0.0003765375,0.004219674,0.8962148,0.0004378376,0.006991165,0.00005874661],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.993701,0.001715279,0.001815787,0.0002340911,0.00007683368,0.0001305114,0.001317132,0.0001176373,0.0008917429],"genre_scores_gemma":[0.9910222,0.001157941,0.001855478,0.0001967495,0.00002847996,0.0003913791,0.001012452,0.00003575551,0.004299666],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001567763,"threshold_uncertainty_score":0.005244672,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01510838187681843,"score_gpt":0.2241137259675797,"score_spread":0.2090053440907613,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}