{"id":"W4362655084","doi":"10.1093/jnci/dju218","title":"Insulin-like Growth Factor Pathway Genetic Polymorphisms, Circulating IGF1 and IGFBP3, and Prostate Cancer Survival","year":2014,"lang":"en","type":"article","venue":"JNCI Journal of the National Cancer Institute","topic":"Growth Hormone and Insulin-like Growth Factors","field":"Medicine","cited_by":30,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University","funders":"","keywords":"IGFBP3; Single-nucleotide polymorphism; Prostate cancer; Hazard ratio; Oncology; Linkage disequilibrium; Internal medicine; SNP; Medicine; Insulin-like growth factor; Proportional hazards model; Cancer; Biology; Bioinformatics; Genotype; Confidence interval; Genetics; Gene; Growth factor","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006193243,0.0002494596,0.0002434749,0.0002348947,0.0001457116,0.0002562765,0.000202642,0.000241439,0.00170281],"category_scores_gemma":[0.001760251,0.0001119749,0.0004836969,0.0004466043,0.0001805837,0.0001150847,0.0002161354,0.0004111691,0.0001206152],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000235396,"about_ca_system_score_gemma":0.0004062143,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.003244047,"about_ca_topic_score_gemma":0.003087104,"domain_scores_codex":[0.9998156,0.00005481777,0.00001192816,0.00005202123,0.00003283285,0.0000328311],"domain_scores_gemma":[0.9992151,0.0002876988,0.000243519,0.00007993102,0.00006018172,0.0001136283],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0009397042,0.00003420256,0.9916056,0.00001855233,0.0002992348,0.00006425573,0.0000230383,0.00101651,0.001343479,0.00003611773,0.0001336807,0.004485538],"study_design_scores_gemma":[0.00003807186,0.0001384773,0.9956198,0.000004295741,0.000199757,0.0002794498,0.00001977265,0.002989155,0.000352964,0.0002057084,0.0001469979,0.000005355424],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9987953,0.0002393557,0.0005747148,0.00003385733,0.000003035908,0.000003625932,0.0002415774,0.00001015441,0.00009844737],"genre_scores_gemma":[0.9993545,0.00005395114,0.0002866128,0.000008380867,0.000003295129,0.000003944641,0.0001962082,0.000001872957,0.00009115206],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003244047,"threshold_uncertainty_score":0.006450295,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04196163223038378,"score_gpt":0.2915429085772753,"score_spread":0.2495812763468915,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}