{"id":"W4362657670","doi":"10.1002/cncr.34778","title":"Impact of bortezomib‐based versus lenalidomide maintenance therapy on outcomes of patients with high‐risk multiple myeloma","year":2023,"lang":"en","type":"article","venue":"Cancer","topic":"Multiple Myeloma Research and Treatments","field":"Medicine","cited_by":11,"is_retracted":false,"has_abstract":true,"ca_institutions":"McMaster University","funders":"National Institute of Allergy and Infectious Diseases; Office of Naval Research; Daiichi Sankyo Company; Legend Biotech; Pharmacyclics; Takeda Oncology; Health Resources and Services Administration; Hamilton Health Sciences Foundation; MorphoSys; Astellas Pharma; Adaptive Biotechnologies; Pfizer; Incyte; Kiadis Pharma; TG Therapeutics; bluebird bio; Medac; Prothena; Jazz Pharmaceuticals; StemCyte; Actinium Pharmaceuticals; CareDx; National Heart, Lung, and Blood Institute; Novartis Pharmaceuticals Corporation; Bristol-Myers Squibb; CSL Behring; National Center for Advancing Translational Sciences; HistoGenetics; Atara Biotherapeutics; Daiichi Sankyo Europe; National Cancer Institute; Gilead Sciences; Sanofi; Amgen; Omeros Corporation; Sanofi Genzyme; Hamilton Health Sciences; GlaxoSmithKline; Mallinckrodt Pharmaceuticals; Astellas Pharma US","keywords":"Lenalidomide; Bortezomib; Medicine; Multiple myeloma; Internal medicine; Maintenance therapy; Oncology; Autologous stem-cell transplantation; Surgery; Chemotherapy","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007274495,0.0001409328,0.0003030295,0.0002318002,0.0002855397,0.000570727,0.0002186555,0.0002743351,0.0007499044],"category_scores_gemma":[0.002478248,0.00007385575,0.0004315365,0.0003186715,0.0002034256,0.0003688529,0.0003847195,0.0005270239,0.00009524755],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007294192,"about_ca_system_score_gemma":0.0005306577,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001085364,"about_ca_topic_score_gemma":0.00230238,"domain_scores_codex":[0.9995589,0.0001347865,0.00005475938,0.00007454574,0.00008782596,0.00008917916],"domain_scores_gemma":[0.9986319,0.0002856105,0.0005894909,0.00003064807,0.00007206448,0.0003903093],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"nonrandomized_trial","study_design_scores_codex":[0.00911482,0.0004547838,0.96252,0.00004744382,0.0003135243,0.00008895377,0.00008983247,0.0003445453,0.0006294007,0.00005304895,0.0004272787,0.02591634],"study_design_scores_gemma":[0.0005199449,0.005672586,0.9910802,0.00003441123,0.0003427063,0.0003496165,0.0001852669,0.0007158245,0.0004700127,0.00009809798,0.0005220155,0.000009300977],"study_design_candidate":"nonrandomized_trial","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9989377,0.0005548936,0.00002133689,0.0001183974,0.00001072804,0.000006277641,0.0000505574,0.000001611334,0.0002984851],"genre_scores_gemma":[0.9996625,0.0001000257,0.00002188469,0.00005620458,0.00001592903,0.000005207538,0.0001023541,6.074845e-7,0.00003514852],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001085364,"threshold_uncertainty_score":0.005292296,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03776128518566816,"score_gpt":0.3495376191272088,"score_spread":0.3117763339415406,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}