{"id":"W4362657801","doi":"10.1161/atvbaha.122.319025","title":"Autoimmune Valvular Carditis Requires Endothelial Cell TNFR1 Expression","year":2023,"lang":"en","type":"article","venue":"Arteriosclerosis Thrombosis and Vascular Biology","topic":"IL-33, ST2, and ILC Pathways","field":"Immunology and Microbiology","cited_by":5,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Institute of Genetics; National Center for Advancing Translational Sciences; National Institute of Allergy and Infectious Diseases; Ministry of Science and Higher Education of the Russian Federation; National Institutes of Health; University of Minnesota; National Heart, Lung, and Blood Institute; National Institute of General Medical Sciences; University of Warwick","keywords":"Proinflammatory cytokine; Tumor necrosis factor alpha; Inflammation; Immunology; Medicine; Endothelial stem cell; Cancer research; Biology","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0005003961,0.0004294015,0.000784698,0.000219933,0.0006828757,0.00004679837,0.0003442405,0.000612524,0.0003088418],"category_scores_gemma":[0.0000685601,0.0003676931,0.0003597061,0.0003211868,0.0004237385,0.0001612381,0.0003713003,0.0003175715,0.001256525],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002999689,"about_ca_system_score_gemma":0.00005432105,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002121687,"about_ca_topic_score_gemma":0.00002093446,"domain_scores_codex":[0.9971833,0.0005399629,0.0005122229,0.0008120616,0.00006736488,0.0008850982],"domain_scores_gemma":[0.9988495,0.0001490243,0.0001640407,0.0006909651,0.00007790315,0.00006857565],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.000006091434,0.00009112351,0.009200213,0.00004399012,0.0002370901,3.559597e-7,0.0008207321,0.000002041709,0.9847616,0.000272099,0.003913886,0.0006507568],"study_design_scores_gemma":[0.002444766,0.0005577453,0.6311029,0.0001103271,0.0001522555,0.000003200261,0.0004438115,0.00001174546,0.1244917,0.000247091,0.2398174,0.0006171332],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9942285,0.0006212879,0.0002099073,0.0001501557,0.001776986,0.0003358802,0.001402355,0.0004079515,0.000866952],"genre_scores_gemma":[0.9876447,0.01087204,0.0001124574,0.0002313169,0.0001431376,0.0001054553,0.0007119495,0.00005599375,0.0001229701],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.86027,"threshold_uncertainty_score":0.9998775,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03107749122913699,"score_gpt":0.2546427259651527,"score_spread":0.2235652347360157,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}