{"id":"W4362657927","doi":"10.1111/jnc.15822","title":"Recent insights into the networking of <i>CLN</i> genes and proteins in mammalian cells","year":2023,"lang":"en","type":"review","venue":"Journal of Neurochemistry","topic":"Lysosomal Storage Disorders Research","field":"Medicine","cited_by":14,"is_retracted":false,"has_abstract":true,"ca_institutions":"Trent University","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research","keywords":"Neurodegeneration; Neuronal ceroid lipofuscinosis; Batten disease; Gene; Biology; Disease; Neuroscience; Genetics; Computational biology; Medicine; Pathology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005279887,0.0005644824,0.0007501077,0.001227012,0.0003421934,0.001505515,0.0005347662,0.0008772071,0.001154522],"category_scores_gemma":[0.0003697392,0.0003457084,0.0006021463,0.001018462,0.0006399515,0.002012968,0.0006276476,0.001211401,0.001034563],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0009648233,"about_ca_system_score_gemma":0.0008187224,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007393337,"about_ca_topic_score_gemma":0.001007607,"domain_scores_codex":[0.9997227,0.00005300066,0.00004786585,0.00005246427,0.00009079653,0.00003317133],"domain_scores_gemma":[0.999759,0.00007330118,0.00006491994,0.00001881629,0.00005691936,0.00002689129],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0003503467,0.0001095208,0.001824414,0.0224138,0.0002068748,0.004046737,0.001440643,0.001964413,0.4060437,0.04114926,0.01796163,0.5024886],"study_design_scores_gemma":[0.00001019376,0.0001825526,0.003260629,0.001322803,0.0001478981,0.003745494,0.0004457315,0.0005702924,0.04116248,0.00869308,0.9404035,0.00005526538],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.007302057,0.9734679,0.005755485,0.002079997,0.000558639,0.00002569068,0.0002441325,0.0001325562,0.01043357],"genre_scores_gemma":[0.02651558,0.9619687,0.005239103,0.001512661,0.0005293618,0.00004119842,0.0004736223,0.00002165225,0.003698162],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.001505515,"threshold_uncertainty_score":0.007000268,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.06502694750998332,"score_gpt":0.3445132339707492,"score_spread":0.2794862864607659,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}