{"id":"W4362671284","doi":"10.1016/j.ajoc.2023.101842","title":"Vitelliform maculopathy in MELAS syndrome","year":2023,"lang":"en","type":"article","venue":"American Journal of Ophthalmology Case Reports","topic":"Mitochondrial Function and Pathology","field":"Biochemistry, Genetics and Molecular Biology","cited_by":3,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Oregon Health and Science University; Research to Prevent Blindness; National Institutes of Health; Foundation Fighting Blindness","keywords":"Maculopathy; Medicine; Mitochondrial encephalomyopathy; Lactic acidosis; Asymptomatic; MELAS syndrome; Fluorescein angiography; Ophthalmology; Mitochondrial myopathy; Retinal; Retinopathy; Internal medicine; Endocrinology; Mitochondrial DNA; Diabetes mellitus; Genetics; Biology","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000738029,0.0001506284,0.0003926155,0.000317695,0.00004343515,0.000007783513,0.00007425447,0.0001220466,0.0001170741],"category_scores_gemma":[0.0002562486,0.0001357966,0.0001659487,0.0004728418,0.0002065281,0.00000614199,0.00006867731,0.0002150703,0.00002583949],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002201057,"about_ca_system_score_gemma":0.0001357054,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00003350496,"about_ca_topic_score_gemma":0.000003998232,"domain_scores_codex":[0.9984373,0.0001798255,0.0006864824,0.0002675609,0.0001302162,0.0002985606],"domain_scores_gemma":[0.9987706,0.00004167198,0.0006350022,0.0002973419,0.0001144671,0.0001409467],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"case_report","study_design_gemma":"case_report","study_design_scores_codex":[0.0001414066,0.00005162513,0.03243837,0.000005236201,0.00005040305,0.9391575,0.00005912842,0.0001675482,0.02612893,0.000005001287,0.0006947783,0.001100021],"study_design_scores_gemma":[0.0002433118,0.001541159,0.006267242,0.00001041538,0.00001730901,0.9851576,0.0003040714,0.000005199848,0.002507989,0.0001107727,0.0037008,0.000134144],"study_design_candidate":"case_report","study_design_consensus":"case_report","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9970375,0.0001732233,0.00009925877,0.0001741677,0.001318587,0.00008291675,0.000003692791,0.000007295037,0.00110333],"genre_scores_gemma":[0.9983824,0.00006647941,0.0005610081,0.00008736071,0.0001770788,0.000006700679,0.00001906921,0.00002242244,0.0006774092],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.04600003,"threshold_uncertainty_score":0.5537625,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01374039305540923,"score_gpt":0.2833689223693259,"score_spread":0.2696285293139167,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}