{"id":"W4362674372","doi":"10.30895/2221-996x-2023-23-1-26-41","title":"Safety and immunogenicity of IMVAMUNE®, a third-generation vaccine based on the modified vaccinia Ankara (MVA) strain","year":2023,"lang":"en","type":"article","venue":"Biological Products Prevention Diagnosis Treatment","topic":"Poxvirus research and outbreaks","field":"Immunology and Microbiology","cited_by":3,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"","keywords":"Medicine; Vaccinia; Smallpox; myalgia; Chills; Smallpox vaccine; Adverse effect; Vaccination; Modified vaccinia Ankara; Immunogenicity; Virology; Attenuated vaccine; Immunology; Surgery; Internal medicine; Immune system","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0008844447,0.0002459701,0.0003602118,0.0001169463,0.0003028136,0.00001859798,0.0001861712,0.0002095844,0.000303226],"category_scores_gemma":[0.0006523172,0.0001329272,0.0001487526,0.000386188,0.0001175303,0.00004918605,0.00008997364,0.0001585739,0.0001507319],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00008419871,"about_ca_system_score_gemma":0.00006998359,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00007841454,"about_ca_topic_score_gemma":0.00003527986,"domain_scores_codex":[0.9976866,0.0009025563,0.0004269496,0.0005304677,0.0000755708,0.000377898],"domain_scores_gemma":[0.9986777,0.0005747276,0.0001639439,0.0004594859,0.00008870109,0.00003544482],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.003199661,0.003297475,0.01377538,0.00004128555,0.0008167202,0.00001212942,0.0002411582,0.0002956408,0.8494242,0.003917606,0.005058204,0.1199205],"study_design_scores_gemma":[0.005306922,0.006465153,0.4291248,0.00007056297,0.0001062491,0.000007068841,0.00008033717,0.0004053225,0.5483748,0.0006062483,0.009122848,0.0003296284],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9909289,0.001986476,0.00003791531,0.005017257,0.0001577536,0.00132736,0.0002672241,0.0001095657,0.0001675167],"genre_scores_gemma":[0.9944989,0.003465963,0.00003026596,0.0001055483,0.00005409387,0.0004123169,0.0008775259,0.00001001506,0.0005453544],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.4153495,"threshold_uncertainty_score":0.5420615,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.08164719609911085,"score_gpt":0.3061261695840588,"score_spread":0.2244789734849479,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}