{"id":"W4362684655","doi":"10.1177/17562848231159452","title":"Is there an optimal sequence of biologic therapies for inflammatory bowel disease?","year":2023,"lang":"en","type":"review","venue":"Therapeutic Advances in Gastroenterology","topic":"Inflammatory Bowel Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":59,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"","keywords":"Medicine; Inflammatory bowel disease; Sequence (biology); Disease; Intensive care medicine; Bioinformatics; Internal medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0004221893,0.0006293182,0.001043759,0.0002042994,0.0000602845,0.00001296691,0.0009126046,0.0003950142,0.00003275644],"category_scores_gemma":[0.00004265035,0.0005280296,0.0005422618,0.00009260207,0.0005817895,0.00002262696,0.0001827075,0.0002342761,0.00001181037],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00004729467,"about_ca_system_score_gemma":0.0002422825,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000001046532,"about_ca_topic_score_gemma":0.00006537809,"domain_scores_codex":[0.9968249,0.0005608897,0.0008939974,0.00087845,0.000144469,0.0006972698],"domain_scores_gemma":[0.9981312,0.00007412577,0.0006352523,0.000913739,0.00009553762,0.0001501263],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.01360493,0.0009927276,0.08341181,0.05538875,0.002785472,0.0003937664,0.0004782476,0.001358206,0.000583645,0.001222729,0.0001286217,0.8396511],"study_design_scores_gemma":[0.002245903,0.002511149,0.008933996,0.003249191,0.0008301541,0.00003792517,0.0001737354,0.000179686,0.0000277597,0.002004712,0.9787176,0.001088205],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.02449959,0.9718897,0.0008884492,0.00002035539,0.0003055094,0.001465643,0.0008727823,0.00004681584,0.00001113107],"genre_scores_gemma":[0.004689333,0.9925259,0.0004466299,0.0002700013,0.0002335753,0.0009264988,0.0007013637,0.0001359878,0.00007074644],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9785889,"threshold_uncertainty_score":0.9997171,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0468488222519881,"score_gpt":0.3577943409847046,"score_spread":0.3109455187327165,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}