{"id":"W4362722926","doi":"10.1002/adhm.202300224","title":"Engineered Curli Nanofilaments as a Self‐Adjuvanted Antigen Delivery Platform","year":2023,"lang":"en","type":"article","venue":"Advanced Healthcare Materials","topic":"RNA Interference and Gene Delivery","field":"Biochemistry, Genetics and Molecular Biology","cited_by":16,"is_retracted":false,"has_abstract":true,"ca_institutions":"PROTEO; Cegep de Saint Hyacinthe; Université du Québec à Montréal","funders":"Fonds de recherche du Québec – Nature et technologies; Natural Sciences and Engineering Research Council of Canada","keywords":"Nanotechnology; Materials science; Immunology; Medicine","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0001974295,0.0002662915,0.0003098156,0.0001108011,0.00013793,0.00004157875,0.0002671802,0.0002210576,0.0001003965],"category_scores_gemma":[0.00005367283,0.0002638527,0.0000806982,0.000200287,0.00002891224,0.00001858239,0.0001714179,0.00006906907,0.0006337162],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002999402,"about_ca_system_score_gemma":0.0001362218,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000195218,"about_ca_topic_score_gemma":0.00004690457,"domain_scores_codex":[0.9982435,0.00005782973,0.0004237308,0.0005043455,0.0001890906,0.0005815104],"domain_scores_gemma":[0.9990797,0.00001443643,0.0001281503,0.0004561103,0.0001678265,0.0001537472],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000227979,0.00002573833,0.0002093731,0.00009305937,0.0000625084,0.00002693556,0.0001357379,0.00003752187,0.9948782,0.00005526818,0.001334637,0.002913003],"study_design_scores_gemma":[0.0006786989,0.0005519239,0.002687797,0.00008983861,0.000009054015,0.00002152555,0.0001897212,0.00001506369,0.9725403,0.0002032158,0.02268814,0.000324746],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9970338,0.0005334198,0.00004038498,0.0003692331,0.001055934,0.0004209994,0.0002205526,0.0001917166,0.0001340004],"genre_scores_gemma":[0.991581,0.004492008,0.000497109,0.001122166,0.0002731473,0.00009358385,0.001177383,0.000053868,0.0007097086],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02233797,"threshold_uncertainty_score":0.9999813,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01574554313406198,"score_gpt":0.2915681886624207,"score_spread":0.2758226455283587,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}