{"id":"W4362723521","doi":"10.1016/j.cellimm.2023.104718","title":"IFN-β activates cytotoxic function of human natural killer cells toward IL-27 and poly(I:C) stimulated PC3 and DU145 cells","year":2023,"lang":"en","type":"article","venue":"Cellular Immunology","topic":"Immune Cell Function and Interaction","field":"Immunology and Microbiology","cited_by":2,"is_retracted":false,"has_abstract":true,"ca_institutions":"Queen's University","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research; Prostate Cancer Fight Foundation","keywords":"DU145; Interleukin 21; Cytotoxic T cell; Biology; Cancer research; Cytokine; Cancer cell; Immune system; Interleukin 12; Lymphokine-activated killer cell; NK-92; Immunology; Cell biology; T cell; Cancer; LNCaP; In vitro; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001090109,0.0003999864,0.0003009978,0.0001135982,0.00007987232,0.0002408274,0.0001133652,0.0001437152,0.001447254],"category_scores_gemma":[0.0001121466,0.0001013961,0.000395562,0.0001254078,0.000147748,0.0001343361,0.0001504014,0.0006395262,0.0003259864],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001689557,"about_ca_system_score_gemma":0.0002094994,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008824713,"about_ca_topic_score_gemma":0.0008014835,"domain_scores_codex":[0.9997972,0.00003813328,0.0000240112,0.00003971748,0.00004573433,0.00005523267],"domain_scores_gemma":[0.9999219,0.00001892987,0.0000153155,0.00001323505,0.00001245282,0.00001825284],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0004734631,0.00006352392,0.0004261684,0.00007419939,0.000008359802,0.00006592811,0.00004444206,0.000173001,0.9967457,0.00004525054,0.00006004203,0.001819863],"study_design_scores_gemma":[0.00004468897,0.0008762443,0.006855348,0.000009168685,0.00001940818,0.0002449091,0.00005855182,0.001251928,0.9892111,0.00003250637,0.001390379,0.000005714158],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9950412,0.0009831507,0.00196183,0.00004513397,0.00005247815,0.00004557524,0.0003873188,0.00003601199,0.001447347],"genre_scores_gemma":[0.9958174,0.0005303982,0.001148181,0.00007696142,0.00001563741,0.00005637276,0.0007039028,0.000008706317,0.00164236],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001447254,"threshold_uncertainty_score":0.004841566,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01216295797356139,"score_gpt":0.2233823151341436,"score_spread":0.2112193571605822,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}