{"id":"W4363677815","doi":"10.3390/cancers15082195","title":"Regulation of Autophagy via Carbohydrate and Lipid Metabolism in Cancer","year":2023,"lang":"en","type":"review","venue":"Cancers","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":47,"is_retracted":false,"has_abstract":true,"ca_institutions":"Research Institute in Oncology and Hematology; University of Alberta; Children's Hospital Research Institute of Manitoba; CancerCare Manitoba; Health Sciences Centre; St. Boniface Hospital; University of Manitoba","funders":"Max Rady College of Medicine, University of Manitoba; CancerCare Manitoba Foundation","keywords":"Autophagy; Organelle; Cell biology; Lipid metabolism; Metabolic pathway; Cancer cell; Biochemistry; Carcinogenesis; Cell metabolism; Metabolism; Biology; Glycolysis; Cell; Carbohydrate metabolism; Chemistry; Lipid droplet; Cancer; Apoptosis","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001157574,0.0002375605,0.001406317,0.0002890098,0.00001760853,0.000004760288,0.00007294067,0.0002083151,0.0001376312],"category_scores_gemma":[0.00001675496,0.0001962994,0.0001930946,0.0005480436,0.00008341137,0.00003829509,0.00002485184,0.0001941045,0.000008921777],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006100087,"about_ca_system_score_gemma":0.001401633,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001021518,"about_ca_topic_score_gemma":0.00008192219,"domain_scores_codex":[0.9988353,0.0000573579,0.0004509603,0.0002985229,0.0001644678,0.0001933743],"domain_scores_gemma":[0.9992837,0.00004621463,0.0002594703,0.0002693874,0.00003923658,0.0001020465],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00003506827,0.00001047393,0.000009521174,0.01722653,0.0004645338,0.00002726072,0.0001741895,0.00003862789,0.0001097963,0.0001458055,0.0002258406,0.9815323],"study_design_scores_gemma":[0.0009116338,0.00004334927,0.001583374,0.01806315,0.001926256,0.00000691662,0.00001331451,0.0003084794,0.0001324295,0.0002094299,0.9765051,0.0002965383],"study_design_candidate":"design_other","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.001241722,0.9972095,0.000004933574,0.00001686909,0.0005580377,0.0006688399,0.00006175309,0.00004184442,0.0001964389],"genre_scores_gemma":[0.000580183,0.9977107,0.00001511542,0.00006007695,0.0003921826,0.0002643961,0.00009292769,0.00006186083,0.0008225307],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9812358,"threshold_uncertainty_score":0.8004859,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04980729623579624,"score_gpt":0.3663446238384224,"score_spread":0.3165373276026262,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}