{"id":"W4364365415","doi":"10.3389/fcimb.2023.1103189","title":"Preliminary evidence for developing safe and efficient fecal microbiota transplantation as potential treatment for aged related cognitive impairments","year":2023,"lang":"en","type":"article","venue":"Frontiers in Cellular and Infection Microbiology","topic":"Gut microbiota and health","field":"Biochemistry, Genetics and Molecular Biology","cited_by":51,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Natural Science Foundation of Guangdong Province","keywords":"Fecal bacteriotherapy; Feces; Cognition; Transplantation; Medicine; Immunology; Intensive care medicine; Biology; Microbiology; Antibiotics; Psychiatry; Internal medicine; Clostridium difficile","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.003119749,0.000474012,0.0008745994,0.0003769122,0.0001879214,0.0007300312,0.00063254,0.001162549,0.00813713],"category_scores_gemma":[0.003011645,0.0001036032,0.001207487,0.0002887319,0.0005233652,0.0005902312,0.0004542391,0.001237541,0.0008332648],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002746371,"about_ca_system_score_gemma":0.001173121,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002459923,"about_ca_topic_score_gemma":0.0005690655,"domain_scores_codex":[0.9994035,0.0003441189,0.00006672232,0.00005612767,0.00007360709,0.0000558903],"domain_scores_gemma":[0.9973111,0.001425816,0.0004450616,0.0001723156,0.0003767028,0.0002688631],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.04711357,0.009801638,0.0125881,0.02030654,0.002034609,0.001134489,0.000223722,0.001112915,0.0523491,0.003938858,0.010005,0.8393915],"study_design_scores_gemma":[0.05026439,0.3805344,0.1533328,0.01771676,0.008735646,0.004845658,0.001099819,0.002310976,0.06640885,0.01085075,0.3037495,0.0001505098],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.4689866,0.4687077,0.01523715,0.02444696,0.001957756,0.00204204,0.002104323,0.0002835213,0.01623397],"genre_scores_gemma":[0.6945105,0.2570111,0.02576742,0.01253321,0.002405719,0.001680936,0.002127094,0.00005783779,0.003906247],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00813713,"threshold_uncertainty_score":0.02722144,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0178508714674698,"score_gpt":0.2913665017664544,"score_spread":0.2735156302989846,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}