{"id":"W4364365415","doi":"10.3389/fcimb.2023.1103189","title":"Preliminary evidence for developing safe and efficient fecal microbiota transplantation as potential treatment for aged related cognitive impairments","year":2023,"lang":"en","type":"article","venue":"Frontiers in Cellular and Infection Microbiology","topic":"Gut microbiota and health","field":"Biochemistry, Genetics and Molecular Biology","cited_by":51,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Natural Science Foundation of Guangdong Province","keywords":"Fecal bacteriotherapy; Feces; Cognition; Transplantation; Medicine; Immunology; Intensive care medicine; Biology; Microbiology; Antibiotics; Psychiatry; Internal medicine; Clostridium difficile","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002705292,0.0001865005,0.0002189494,0.0001691218,0.0002148634,0.00001701756,0.00003734854,0.000294464,0.000002227649],"category_scores_gemma":[0.00003976643,0.000183018,0.00008151677,0.0001089687,0.0001101372,0.000007111714,0.00002982145,0.00006549084,0.00000273977],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00006762018,"about_ca_system_score_gemma":0.0000936807,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00004585853,"about_ca_topic_score_gemma":0.00002154822,"domain_scores_codex":[0.9987942,0.0001069415,0.0002730256,0.0004814715,0.00001682464,0.0003275422],"domain_scores_gemma":[0.9996923,0.0000469666,0.0000870219,0.00007537191,0.00005159706,0.00004678138],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001402434,0.00006796559,0.005137831,0.000193203,0.00008784528,0.000005843071,0.0003753034,0.00006630015,0.9894443,0.000006280783,0.0008702413,0.002342435],"study_design_scores_gemma":[0.01816556,0.00931679,0.08622219,0.0005079439,0.0004196023,0.0007649023,0.0006804542,0.00176777,0.8722537,0.0002307295,0.008658844,0.001011546],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9565499,0.001640008,0.03953207,0.0001359776,0.0006923723,0.001289004,0.0001359331,0.00001875152,0.000006004605],"genre_scores_gemma":[0.9907923,0.004428505,0.001871304,0.0001064113,0.00005864507,0.0001377194,0.002275789,0.00002179893,0.0003075374],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1171906,"threshold_uncertainty_score":0.7463259,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0178508714674698,"score_gpt":0.2913665017664544,"score_spread":0.2735156302989846,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}