{"id":"W4365136030","doi":"10.1007/s00417-023-06041-0","title":"Anterior segment phenotypic changes in late-onset retinal degeneration with Ser163Arg mutation in CTRP5/C1QTNF5","year":2023,"lang":"en","type":"article","venue":"Graefe s Archive for Clinical and Experimental Ophthalmology","topic":"Retinal Development and Disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":false,"ca_institutions":"McGill University; University of Toronto","funders":"University of California, San Diego; Foundation Fighting Blindness; Pan-American Association of Ophthalmology; Wellcome Trust; Research to Prevent Blindness; International Society of Ocular Oncology","keywords":"Retinal degeneration; Retinal; Phenotype; Mutation; Retina; Medicine; Ophthalmology; Degeneration (medical); Biology; Genetics; Neuroscience; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002441604,0.00108661,0.0004332375,0.001084557,0.0005893006,0.0003792372,0.0005637275,0.0015583,0.005469915],"category_scores_gemma":[0.0007225237,0.000227455,0.000812182,0.0004781851,0.0008521009,0.0003140192,0.0004487197,0.0005840312,0.001138475],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004079601,"about_ca_system_score_gemma":0.0002393996,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.003690592,"about_ca_topic_score_gemma":0.00244076,"domain_scores_codex":[0.9996949,0.00003784749,0.00005630328,0.00008588174,0.00006877875,0.00005628917],"domain_scores_gemma":[0.9994912,0.0001233805,0.0001774443,0.00002731386,0.00005015347,0.0001304392],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"case_report","study_design_gemma":"observational","study_design_scores_codex":[0.001333845,0.0002160107,0.01524159,0.0001412962,0.00009843905,0.7411448,0.0004084113,0.000341798,0.2352266,0.0004610284,0.0007329179,0.00465319],"study_design_scores_gemma":[0.0002905149,0.001218258,0.2517936,0.00008775546,0.0003810288,0.7022588,0.0004361209,0.003133715,0.03618851,0.0005837666,0.003513704,0.0001142114],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9939009,0.0004980596,0.0009273795,0.0002487463,0.0001020685,0.00005412703,0.0006109158,0.00009997728,0.003557912],"genre_scores_gemma":[0.9972197,0.0001303673,0.0005084185,0.0001297923,0.00004349157,0.00001044479,0.0002456392,0.00002850186,0.001683705],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.005469915,"threshold_uncertainty_score":0.01829869,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03507821965335291,"score_gpt":0.3482963952209132,"score_spread":0.3132181755675603,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}