{"id":"W4365136859","doi":"10.1101/2023.04.11.536425","title":"Minute virus of mice is oncolytic for pancreatic cancer cells with mesenchymal phenotype","year":2023,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"Virus-based gene therapy research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"University of British Columbia; Inserm Transfert; Fondation ARC pour la Recherche sur le Cancer; Institut National de la Santé et de la Recherche Médicale; Alliance Nationale pour les Sciences de la Vie et de la Santé","keywords":"Oncolytic virus; Pancreatic cancer; Mesenchymal stem cell; Biology; Cancer research; Phenotype; Cancer; Virotherapy; In vivo; Virology; Immunology; Virus; Cell biology; Gene; Genetics","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002697871,0.0005314418,0.0002324662,0.0005264352,0.0001978776,0.0004118734,0.0002577967,0.0005429359,0.002018291],"category_scores_gemma":[0.0001480429,0.0002252159,0.0003418276,0.0001939948,0.0003574983,0.0002625671,0.0002835231,0.0009997264,0.0007470125],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002443616,"about_ca_system_score_gemma":0.0001939112,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004320652,"about_ca_topic_score_gemma":0.0004008265,"domain_scores_codex":[0.9997546,0.00004195911,0.00002226957,0.0000625344,0.00006446766,0.00005418439],"domain_scores_gemma":[0.9998436,0.00003258584,0.00005436231,0.00002487397,0.000007586937,0.00003690481],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001610973,0.00002836789,0.0001590611,0.00002837471,0.000006102363,0.0000458968,0.00002261878,0.00006958893,0.9972473,0.0009182976,0.0001492814,0.001164006],"study_design_scores_gemma":[0.00002239542,0.000243645,0.0009059559,0.000008557987,0.000009670798,0.0003206425,0.0000155936,0.0007988208,0.9903503,0.0001888207,0.007130875,0.000004604034],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9531024,0.002904723,0.03108947,0.0006686116,0.000226701,0.0001601284,0.003057146,0.0008206423,0.007970203],"genre_scores_gemma":[0.959752,0.001561297,0.01829984,0.0001443298,0.00004913615,0.0001518731,0.003597911,0.0002426101,0.01620103],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002018291,"threshold_uncertainty_score":0.006751895,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02490688450775766,"score_gpt":0.2763585927156527,"score_spread":0.251451708207895,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}