{"id":"W4365455664","doi":"10.1101/2023.04.12.536615","title":"G-quadruplexe as a structural modulator of Intron Retention upon viral infection","year":2023,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"RNA Research and Splicing","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Sherbrooke","funders":"","keywords":"Intron; RNA splicing; Biology; SR protein; Gene; Alternative splicing; RNA; Mutant; Cell biology; Genetics; Computational biology; Gene isoform","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001142791,0.0001029803,0.0001424471,0.0001121809,0.0001173593,0.0001926488,0.0001122052,0.0002111833,0.001142129],"category_scores_gemma":[0.0001342823,0.00007629016,0.00009316015,0.00006571677,0.0001772863,0.0001152387,0.0001253256,0.0003274906,0.000266265],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001599585,"about_ca_system_score_gemma":0.00006731423,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001552371,"about_ca_topic_score_gemma":0.0001641577,"domain_scores_codex":[0.9999313,0.0000135561,0.000004228835,0.00001925908,0.00001697792,0.00001478501],"domain_scores_gemma":[0.9998994,0.00002614445,0.000035973,0.000007962648,0.000011577,0.00001897606],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0000551807,0.000007913083,0.0002258873,0.00001466857,0.000001669988,0.00002499938,0.00001249745,0.00004457178,0.9989727,0.00005761595,0.00002321607,0.0005591508],"study_design_scores_gemma":[0.000009738529,0.0001850548,0.01043937,0.000007008341,0.000007184817,0.0001921623,0.00003397385,0.003199244,0.9845919,0.0002648786,0.001061513,0.000007974938],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9950158,0.0007314719,0.003075904,0.0000842848,0.00002213385,0.00001207238,0.0001448519,0.00008111807,0.0008323163],"genre_scores_gemma":[0.9982895,0.00009897708,0.0009565521,0.00003822499,0.000004637403,0.000006596512,0.00009440461,0.00001063944,0.0005003936],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001142129,"threshold_uncertainty_score":0.003820777,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01481480281228029,"score_gpt":0.2563384004447172,"score_spread":0.2415235976324369,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}