{"id":"W4365479643","doi":"10.1164/rccm.202303-0614ed","title":"The ABCs and DEGs (Differentially Expressed Genes) of Airway Hyperresponsiveness","year":2023,"lang":"en","type":"letter","venue":"American Journal of Respiratory and Critical Care Medicine","topic":"Asthma and respiratory diseases","field":"Medicine","cited_by":2,"is_retracted":false,"has_abstract":true,"ca_institutions":"McMaster University; University of Saskatchewan","funders":"National Heart, Lung, and Blood Institute","keywords":"Medicine; Airway hyperresponsiveness; Gene; Immunology; Genetics; Computational biology; Asthma; Biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.004688807,0.000592599,0.001225618,0.00065842,0.002372797,0.00218832,0.001065969,0.02032422,0.005391684],"category_scores_gemma":[0.02029341,0.0006249275,0.0008729845,0.0006090205,0.002406227,0.002050599,0.001212804,0.02658086,0.007666934],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.002641157,"about_ca_system_score_gemma":0.003075093,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.003978782,"about_ca_topic_score_gemma":0.007369305,"domain_scores_codex":[0.9974691,0.0009483453,0.0004122352,0.000318491,0.0006559092,0.0001960154],"domain_scores_gemma":[0.9846635,0.008565569,0.0007164681,0.0005128741,0.00428919,0.001252386],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00007896127,0.00001973034,0.000594511,0.00003131653,0.000009369611,0.0005247341,0.00003664823,0.00002536707,0.0001900537,0.001490231,0.9854811,0.0115179],"study_design_scores_gemma":[0.0003396345,0.0001396874,0.00389404,0.0004907012,0.0000552988,0.003385677,0.0003082532,0.0008101972,0.0007886022,0.01683022,0.9728652,0.00009252032],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"commentary","genre_gemma":"commentary","genre_scores_codex":[0.0004084049,0.001820965,0.0002185777,0.9701911,0.02525723,0.00001313875,0.000113413,0.00004793943,0.001929224],"genre_scores_gemma":[0.005091366,0.002026956,0.0005313906,0.9242696,0.06056147,0.00004651261,0.00009554423,0.00002978993,0.007347376],"genre_candidate":"commentary","genre_consensus":"commentary","teacher_disagreement_score":0.02032422,"threshold_uncertainty_score":0.02479714,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01982747087714817,"score_gpt":0.3048998876083326,"score_spread":0.2850724167311844,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}