{"id":"W4365509412","doi":"10.1093/evlett/qrad013","title":"Sex-biased gene expression at single-cell resolution: cause and consequence of sexual dimorphism","year":2023,"lang":"en","type":"article","venue":"Evolution Letters","topic":"Single-cell and spatial transcriptomics","field":"Biochemistry, Genetics and Molecular Biology","cited_by":42,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Biology; Sexual dimorphism; Gene; Gene expression; Sex characteristics; Transcriptome; Gene expression profiling; Genetics; Cell type; Regulation of gene expression; Phenotype; Evolutionary biology; Cell; Zoology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001369296,0.0001380264,0.0001322359,0.00006639655,0.0001208789,0.000009859576,0.00009799741,0.000123614,0.00001091186],"category_scores_gemma":[0.00003345669,0.0001431318,0.00003868702,0.0001194155,0.0002212584,0.000006775107,0.00008290717,0.00006795475,0.00001217872],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00004945264,"about_ca_system_score_gemma":0.00002912979,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00006704832,"about_ca_topic_score_gemma":0.000019043,"domain_scores_codex":[0.9989831,0.00007717415,0.0002110912,0.0003474721,0.0001494443,0.0002316918],"domain_scores_gemma":[0.9995099,0.00002251956,0.00008791201,0.0002660287,0.00003683771,0.00007683744],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00009170978,0.0000369877,0.003431879,0.00003429157,0.00001267904,0.00001955774,0.0000772424,0.0009723135,0.9889644,0.00000348983,0.00630908,0.0000463724],"study_design_scores_gemma":[0.0008190236,0.0001937426,0.00284755,0.00001864081,0.00002225829,0.00004175624,0.00004386243,0.0007596817,0.9937773,0.00001129727,0.001266262,0.0001986085],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9917717,0.000378295,0.006856828,0.0005200671,0.0002080006,0.0001209846,0.00004775214,0.0000391702,0.00005719584],"genre_scores_gemma":[0.9976783,0.00004824602,0.0007094969,0.0003833032,0.0001421148,0.000009263241,0.0001820503,0.00002005372,0.0008271492],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.006147331,"threshold_uncertainty_score":0.5836747,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02379354870091078,"score_gpt":0.2212045336426283,"score_spread":0.1974109849417176,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}