{"id":"W4365512439","doi":"10.1016/j.jaip.2023.04.002","title":"Intravenous Immunoglobulin: Mechanism of Action in Autoimmune and Inflammatory Conditions","year":2023,"lang":"en","type":"article","venue":"The Journal of Allergy and Clinical Immunology In Practice","topic":"Platelet Disorders and Treatments","field":"Medicine","cited_by":57,"is_retracted":false,"has_abstract":false,"ca_institutions":"McGill University Health Centre","funders":"Canadian Institutes of Health Research; Fonds de dotation CSL Behring pour la recherche","keywords":"Medicine; Immunology; Antibody; Mechanism (biology); Effector; Immune system; Acquired immune system; Mechanism of action; Immunoglobulin G; Innate immune system; Biology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005355829,0.000377406,0.0004423846,0.0006045598,0.0002215087,0.001120683,0.0003990753,0.001473288,0.002108556],"category_scores_gemma":[0.0005433353,0.0001090416,0.0003237046,0.0003313623,0.0005155312,0.0004954136,0.0004008686,0.0009041965,0.0004358464],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005090396,"about_ca_system_score_gemma":0.0003793057,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003293583,"about_ca_topic_score_gemma":0.0002531667,"domain_scores_codex":[0.9997062,0.0001225221,0.00001775281,0.00002658823,0.00006974183,0.00005720465],"domain_scores_gemma":[0.999796,0.00007258285,0.00006009124,0.00001128075,0.00001843115,0.00004162279],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.007311685,0.00123084,0.03023018,0.002639754,0.0004676545,0.01672777,0.0005189325,0.001114128,0.193952,0.03488585,0.01090326,0.700018],"study_design_scores_gemma":[0.005653022,0.02806106,0.2556302,0.002296991,0.001845574,0.1263313,0.001171642,0.008611662,0.1364832,0.04147553,0.3922591,0.000180759],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.3680031,0.582589,0.008869439,0.007385693,0.001391836,0.0002272557,0.000181323,0.0002415247,0.03111086],"genre_scores_gemma":[0.9227836,0.06630187,0.002613193,0.001513193,0.001492058,0.00009322711,0.00006765445,0.00001494879,0.005120359],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.002108556,"threshold_uncertainty_score":0.007053792,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03050237966644418,"score_gpt":0.3600605999629193,"score_spread":0.3295582202964751,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}