{"id":"W4365513174","doi":"10.1158/1538-7445.am2023-ct061","title":"Abstract CT061: TRIDENT phase 3 study (EF-32): First-line Tumor Treating Fields (TTFields; 200 kHz) therapy concomitant with chemo-radiation, followed by maintenance TTFields/temozolomide in newly diagnosed glioblastoma","year":2023,"lang":"en","type":"article","venue":"Cancer Research","topic":"Glioma Diagnosis and Treatment","field":"Medicine","cited_by":4,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Montréal","funders":"","keywords":"Medicine; Concomitant; Temozolomide; Internal medicine; Radiation therapy; Oncology; Adverse effect; Phases of clinical research; Surgery; Clinical trial","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001361431,0.001339918,0.001321538,0.0005170341,0.0005177927,0.0009169967,0.0008745198,0.001171987,0.006042963],"category_scores_gemma":[0.0006172277,0.0003870541,0.001330526,0.0005413116,0.0008130539,0.000748759,0.0003143687,0.003504715,0.001299371],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001129994,"about_ca_system_score_gemma":0.002300052,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001995877,"about_ca_topic_score_gemma":0.006044762,"domain_scores_codex":[0.9997556,0.00009490568,0.00001505416,0.00005010917,0.00003094547,0.00005338032],"domain_scores_gemma":[0.9995492,0.00003742972,0.000104264,0.00004128775,0.00004171328,0.0002261043],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"nonrandomized_trial","study_design_scores_codex":[0.6699229,0.07564344,0.006874745,0.001991853,0.001725537,0.0004683883,0.0003553934,0.003467327,0.09407265,0.0008289409,0.02038732,0.1242614],"study_design_scores_gemma":[0.5361786,0.4295827,0.01189347,0.0001623159,0.0007368094,0.0007493009,0.00008558031,0.001317994,0.009823924,0.0005399292,0.008868766,0.00006048354],"study_design_candidate":"nonrandomized_trial","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9792264,0.004297538,0.001120817,0.001186704,0.0002872161,0.004479694,0.004864702,0.0002613295,0.004275783],"genre_scores_gemma":[0.9681342,0.003767918,0.004185611,0.001987285,0.0002229095,0.005437967,0.009341445,0.0001050641,0.00681764],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.006042963,"threshold_uncertainty_score":0.02021569,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05033569187163088,"score_gpt":0.3974147877661319,"score_spread":0.347079095894501,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}