{"id":"W4366090741","doi":"10.3390/pathogens12040604","title":"Development of a High-Throughput Urosepsis Mouse Model","year":2023,"lang":"en","type":"article","venue":"Pathogens","topic":"Sepsis Diagnosis and Treatment","field":"Medicine","cited_by":3,"is_retracted":false,"has_abstract":true,"ca_institutions":"Vancouver General Hospital; University of British Columbia","funders":"Canadian Institutes of Health Research; Deutsche Forschungsgemeinschaft; British Columbia Knowledge Development Fund; Michael Smith Health Research BC","keywords":"Proinflammatory cytokine; Sepsis; Spleen; Proteus mirabilis; Chemokine; Urine; Medicine; Urinary system; Saline; Biology; Andrology; Internal medicine; Urology; Immunology; Inflammation; Bacteria; Staphylococcus aureus","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001206966,0.0001267045,0.0002807293,0.0001157997,0.00005610353,0.000004761876,0.00005065324,0.00005524373,0.00007297759],"category_scores_gemma":[0.00004320525,0.0001029431,0.00009844437,0.0002597331,0.00002327158,0.00002189261,0.00005664654,0.0000458776,0.0002668274],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00007143887,"about_ca_system_score_gemma":0.0001250779,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001276719,"about_ca_topic_score_gemma":0.00001256089,"domain_scores_codex":[0.9989976,0.00001047365,0.0002700631,0.0002354982,0.0002580107,0.000228396],"domain_scores_gemma":[0.9994462,0.00003680344,0.00005780493,0.0002909247,0.00006318901,0.000105035],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002608939,0.004570891,0.08832857,0.000581286,0.00163909,0.0004226054,0.01654837,0.003602489,0.7559139,0.006743569,0.01873855,0.1026498],"study_design_scores_gemma":[0.004257726,0.0003005413,0.1785136,0.0001788085,0.000499159,0.000019195,0.0007308798,0.009664855,0.7941393,0.0005741611,0.01063834,0.000483375],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9978256,0.00007800785,0.0004025234,0.0003542448,0.00005739443,0.0002298423,0.00006394576,0.0001286999,0.0008596989],"genre_scores_gemma":[0.963812,0.0001369058,0.03426579,0.0002290498,0.00002749102,0.0001047546,0.0001086149,0.0000287895,0.00128659],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1021664,"threshold_uncertainty_score":0.4197896,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1407704632434988,"score_gpt":0.3426118793620747,"score_spread":0.2018414161185759,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}