{"id":"W4366090741","doi":"10.3390/pathogens12040604","title":"Development of a High-Throughput Urosepsis Mouse Model","year":2023,"lang":"en","type":"article","venue":"Pathogens","topic":"Sepsis Diagnosis and Treatment","field":"Medicine","cited_by":3,"is_retracted":false,"has_abstract":true,"ca_institutions":"Vancouver General Hospital; University of British Columbia","funders":"Canadian Institutes of Health Research; Deutsche Forschungsgemeinschaft; British Columbia Knowledge Development Fund; Michael Smith Health Research BC","keywords":"Proinflammatory cytokine; Sepsis; Spleen; Proteus mirabilis; Chemokine; Urine; Medicine; Urinary system; Saline; Biology; Andrology; Internal medicine; Urology; Immunology; Inflammation; Bacteria; Staphylococcus aureus","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001653295,0.001439412,0.001673517,0.001683362,0.0005647748,0.001090599,0.001424915,0.001720282,0.002796239],"category_scores_gemma":[0.0005278765,0.0008132124,0.001392339,0.0007145617,0.000505327,0.0009159571,0.0008927194,0.002914815,0.001632805],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005057752,"about_ca_system_score_gemma":0.0005079284,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006313223,"about_ca_topic_score_gemma":0.0008843977,"domain_scores_codex":[0.9984816,0.0002763526,0.0001825752,0.0002990028,0.0005024203,0.0002581064],"domain_scores_gemma":[0.9990757,0.0001101316,0.0002122977,0.0001528111,0.0001545475,0.0002944868],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0008979726,0.001198792,0.0006030859,0.0002080662,0.00006276831,0.0002180445,0.00008456393,0.0007069524,0.9915648,0.0003732762,0.001101007,0.002980694],"study_design_scores_gemma":[0.0005455308,0.008147029,0.005232242,0.00008576393,0.0002506771,0.001217276,0.0001005095,0.01046469,0.9594477,0.0003927049,0.01403929,0.00007651987],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8649945,0.00422196,0.1119472,0.001247258,0.0007003358,0.002105696,0.008324577,0.002943179,0.003515407],"genre_scores_gemma":[0.8533564,0.006240383,0.09702941,0.0009991127,0.0001786116,0.007617406,0.01614354,0.0004872483,0.01794785],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002796239,"threshold_uncertainty_score":0.009354353,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1407704632434988,"score_gpt":0.3426118793620747,"score_spread":0.2018414161185759,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}