{"id":"W4366292016","doi":"10.21203/rs.3.rs-2794960/v1","title":"Development and characterization of a fecal-induced peritonitis model of murine sepsis: results from a multi-laboratory study and iterative modification of experimental conditions","year":2023,"lang":"en","type":"preprint","venue":"Research Square","topic":"Clostridium difficile and Clostridium perfringens research","field":"Medicine","cited_by":7,"is_retracted":false,"has_abstract":true,"ca_institutions":"Lawson Health Research Institute; Western University; University of Alberta; University of Calgary; Royal Alexandra Hospital; Thrombosis and Atherosclerosis Research Institute; University of Ottawa; McMaster University; University of Manitoba; Ottawa Hospital","funders":"Ottawa Hospital Anesthesia Alternate Funds Association; Manitoba Medical Service Foundation; McMaster University; Canadian Institutes of Health Research; Royal Alexandra Hospital Foundation; University of Ottawa","keywords":"Peritonitis; Feces; Sepsis; Medicine; Internal medicine; Biology; Microbiology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.003049441,0.00111576,0.0008915841,0.000805722,0.0004795987,0.0008388079,0.0007133252,0.0007460727,0.0005591076],"category_scores_gemma":[0.001001872,0.000329945,0.001031113,0.0003800242,0.0006678979,0.000602894,0.0008035318,0.001670145,0.0003373247],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005477024,"about_ca_system_score_gemma":0.0006522332,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007159843,"about_ca_topic_score_gemma":0.001131855,"domain_scores_codex":[0.9978551,0.0005856832,0.0002698914,0.0004125212,0.0005801376,0.0002966598],"domain_scores_gemma":[0.9979329,0.0002120204,0.000588471,0.0003407584,0.0005388063,0.0003869887],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003398671,0.0007566014,0.001137851,0.00006705866,0.00002411802,0.00004936345,0.00007298404,0.0001336874,0.9957507,0.00004029792,0.00005869322,0.001568886],"study_design_scores_gemma":[0.0001268529,0.01347285,0.01941118,0.00002751319,0.0001870993,0.0004366079,0.0001506339,0.002333002,0.9622081,0.00007222588,0.001529196,0.00004473888],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9663472,0.0006736055,0.03047566,0.0001411465,0.00006346397,0.0008380418,0.0006566605,0.0002044311,0.000599751],"genre_scores_gemma":[0.930609,0.0008960309,0.06196484,0.0002401062,0.00004018904,0.001800956,0.002563009,0.0001227668,0.001763121],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003049441,"threshold_uncertainty_score":0.01612723,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.2130681778298358,"score_gpt":0.4388629293660206,"score_spread":0.2257947515361848,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}